Technology Process of C21H30F2O
There total 16 articles about C21H30F2O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 10 steps
1: pyridinium chlorochromate / dichloromethane / 0 °C
2: oxygen; copper(l) chloride; palladium dichloride / water; N,N-dimethyl-formamide / 20 °C
3: potassium hydroxide / methanol; water / 65 °C
4: palladium on carbon; hydrogen / ethyl acetate / 20 °C
5: potassium tert-butylate / tetrahydrofuran / 0 °C
6: palladium on carbon; hydrogen / ethyl acetate / 20 °C
7: sulfuric acid / tetrahydrofuran; water / 40 °C
8: n-butyllithium / diethyl ether / -78 °C
9: toluene-4-sulfonic acid / benzene / Reflux
10: palladium on carbon; hydrogen / ethyl acetate / 20 °C
With
n-butyllithium; sulfuric acid; palladium on carbon; potassium tert-butylate; hydrogen; oxygen; toluene-4-sulfonic acid; pyridinium chlorochromate; copper(l) chloride; potassium hydroxide; palladium dichloride;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; benzene;
2: Wacker oxidation / 5: Wittig reaction;
DOI:10.1055/s-0030-1260551
- Guidance literature:
-
Multi-step reaction with 3 steps
1: n-butyllithium / diethyl ether / -78 °C
2: toluene-4-sulfonic acid / benzene / Reflux
3: palladium on carbon; hydrogen / ethyl acetate / 20 °C
With
n-butyllithium; palladium on carbon; hydrogen; toluene-4-sulfonic acid;
In
diethyl ether; ethyl acetate; benzene;
DOI:10.1055/s-0030-1260551
- Guidance literature:
-
Multi-step reaction with 9 steps
1: oxygen; copper(l) chloride; palladium dichloride / water; N,N-dimethyl-formamide / 20 °C
2: potassium hydroxide / methanol; water / 65 °C
3: palladium on carbon; hydrogen / ethyl acetate / 20 °C
4: potassium tert-butylate / tetrahydrofuran / 0 °C
5: palladium on carbon; hydrogen / ethyl acetate / 20 °C
6: sulfuric acid / tetrahydrofuran; water / 40 °C
7: n-butyllithium / diethyl ether / -78 °C
8: toluene-4-sulfonic acid / benzene / Reflux
9: palladium on carbon; hydrogen / ethyl acetate / 20 °C
With
n-butyllithium; sulfuric acid; palladium on carbon; potassium tert-butylate; hydrogen; oxygen; toluene-4-sulfonic acid; copper(l) chloride; potassium hydroxide; palladium dichloride;
In
tetrahydrofuran; methanol; diethyl ether; water; ethyl acetate; N,N-dimethyl-formamide; benzene;
1: Wacker oxidation / 4: Wittig reaction;
DOI:10.1055/s-0030-1260551