Technology Process of N-[(5-cyclohexyl-1,2-oxazol-3-yl)methyl]adamantan-1-amine
There total 4 articles about N-[(5-cyclohexyl-1,2-oxazol-3-yl)methyl]adamantan-1-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / methanol / Inert atmosphere
2: carbon tetrabromide; triphenylphosphine / dichloromethane / Inert atmosphere
3: triethylamine; cesium iodide / isopropyl alcohol / Inert atmosphere; Reflux
With
sodium tetrahydroborate; carbon tetrabromide; triethylamine; triphenylphosphine; cesium iodide;
In
methanol; dichloromethane; isopropyl alcohol;
DOI:10.1021/acs.jmedchem.7b01536
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hydroxylamine hydrochloride / methanol / 50 °C / Inert atmosphere
2: sodium tetrahydroborate / methanol / Inert atmosphere
3: carbon tetrabromide; triphenylphosphine / dichloromethane / Inert atmosphere
4: triethylamine; cesium iodide / isopropyl alcohol / Inert atmosphere; Reflux
With
sodium tetrahydroborate; carbon tetrabromide; hydroxylamine hydrochloride; triethylamine; triphenylphosphine; cesium iodide;
In
methanol; dichloromethane; isopropyl alcohol;
DOI:10.1021/acs.jmedchem.7b01536
- Guidance literature:
-
Multi-step reaction with 2 steps
1: carbon tetrabromide; triphenylphosphine / dichloromethane / Inert atmosphere
2: triethylamine; cesium iodide / isopropyl alcohol / Inert atmosphere; Reflux
With
carbon tetrabromide; triethylamine; triphenylphosphine; cesium iodide;
In
dichloromethane; isopropyl alcohol;
DOI:10.1021/acs.jmedchem.7b01536
