(1R,2R)-trans-cyclohexanediol mono-p-dimethylaminophenylacetate

Base Information

• Chemical Name: (1R,2R)-trans-cyclohexanediol mono-p-dimethylaminophenylacetate
• CAS No.: 139670-49-8
• Molecular Formula: C₁₆H₂₃NO₃
• Molecular Weight: 277.364
• Mol file: 139670-49-8.mol

Synonyms:

Chemical Property of (1R,2R)-trans-cyclohexanediol mono-p-dimethylaminophenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (1R,2R)-trans-cyclohexanediol mono-p-dimethylaminophenylacetate

There total 1 articles about (1R,2R)-trans-cyclohexanediol mono-p-dimethylaminophenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R,2R)-trans-1,2-cyclohexanediol (1072-86-2,1460-57-7,1792-81-0,54383-22-1,57794-08-8,931-17-9) + 2-[4-(dimethylamino)phenyl]acetic acid (17078-28-3) → (1R,2R)-trans-cyclohexanediol mono-p-dimethylaminophenylacetate (139670-49-8)

Guidance literature:

With 4 A molecular sieve; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,1'-carbonyldiimidazole; Multistep reaction; 1) DMSO, 40 deg C, 10 min, 2) 40-50 deg C;

DOI:10.1016/S0040-4020(01)80716-X

upstream raw materials:

(1R,2R)-trans-1,2-cyclohexanediol

2-[4-(dimethylamino)phenyl]acetic acid