Technology Process of (2RS,3RS,6RS,7SR)-1-benzyloxy-8-methoxy-3,7-dimethyloctane-2,6-diol
There total 6 articles about (2RS,3RS,6RS,7SR)-1-benzyloxy-8-methoxy-3,7-dimethyloctane-2,6-diol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 2 steps
1: 1.) tert-butyl hydroperoxide, salicylic acid, selenium dioxide, 2.) sodium borohydride, 3.) sodium hydride / 1.) methylene chloride, room temp., 2 d, 2.) 95 percent ethanol, overnight, 3.) ether, reflux, overnight
2: 1.) thexylborane, 2.) 3 M aq. NaOH, 50 percent aq. H2O2 / 1.) THF, -10 deg C, 2 h, 2.) overnight
With
tert.-butylhydroperoxide; sodium hydroxide; sodium tetrahydroborate; selenium(IV) oxide; thexylborane; dihydrogen peroxide; sodium hydride; salicylic acid;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) tert-butyl hydroperoxide, salicylic acid, selenium dioxide, 2.) sodium borohydride, 3.) sodium hydride / 1.) methylene chloride, room temp., 2 d, 2.) 95 percent ethanol, overnight, 3.) ether, reflux, overnight
2: 1.) thexylborane, 2.) 3 M aq. NaOH, 50 percent aq. H2O2 / 1.) THF, -10 deg C, 2 h, 2.) overnight
With
tert.-butylhydroperoxide; sodium hydroxide; sodium tetrahydroborate; selenium(IV) oxide; thexylborane; dihydrogen peroxide; sodium hydride; salicylic acid;
- Guidance literature:
-
With
sodium hydroxide; thexylborane; dihydrogen peroxide;
Yield given. Multistep reaction. Yields of byproduct given;
1.) THF, -10 deg C, 2 h, 2.) overnight;
