4-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-[(trityloxy)methyl]dihydrofuran-2(3H)-one (non-preferred name)

Base Information

Chemical Name:4-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-[(trityloxy)methyl]dihydrofuran-2(3H)-one (non-preferred name)
CAS No.:76236-33-4
Molecular Formula:C37H38 O6 S2
Molecular Weight:642.824
Hs Code.:

Synonyms:2(3H)-Furanone,dihydro-4-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-[(triphenylmethoxy)methyl]-,(4S-trans)-; NSC 332052

Suppliers and Price of 4-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-[(trityloxy)methyl]dihydrofuran-2(3H)-one (non-preferred name)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 4-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-[(trityloxy)methyl]dihydrofuran-2(3H)-one (non-preferred name)

Chemical Property:

Vapor Pressure:2.59E-23mmHg at 25°C
Boiling Point:765°C at 760 mmHg
Flash Point:387.9°C
Density:1.232g/cm³

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-[(trityloxy)methyl]dihydrofuran-2(3H)-one (non-preferred name)

There total 5 articles about 4-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-[(trityloxy)methyl]dihydrofuran-2(3H)-one (non-preferred name) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73968-62-4
(5S)-5-[(trityloxy)methyl]tetrahydro-2-furanone

: 76236-33-4
(3S,4S)-(+)-3-(2-(3,4,5-trimethoxyphenyl)-1,3-dithiane-2-yl)-4-trityloxymethyl-butan-4-olide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, -78 degC, 35 min; 2.) THF, -78 degC, 1.5 h

2: 87 percent / 18-crown-6 / H₂O; ethyl acetate / 14 h / 50 °C

3: 1.) n-BuLi / 1.) n-hexane, THF, -78 degC, 30 min; 2.) THF, -78 degC, 2 h

With n-butyllithium; lithium diisopropyl amide; 18-crown-6 ether; In water; ethyl acetate;
DOI:10.1016/S0040-4020(01)82416-9

Reference yield:

: 76236-31-2,92232-55-8,92232-56-9
(4S)-(+)-2-phenylseleno-4-trityloxymethyl-butan-4-olide

: 76236-33-4
(3S,4S)-(+)-3-(2-(3,4,5-trimethoxyphenyl)-1,3-dithiane-2-yl)-4-trityloxymethyl-butan-4-olide

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / 18-crown-6 / H₂O; ethyl acetate / 14 h / 50 °C

2: 1.) n-BuLi / 1.) n-hexane, THF, -78 degC, 30 min; 2.) THF, -78 degC, 2 h

With n-butyllithium; 18-crown-6 ether; In water; ethyl acetate;
DOI:10.1016/S0040-4020(01)82416-9

Reference yield:

: 76236-31-2,92232-55-8,92232-56-9
(S)-3-Phenylselanyl-5-trityloxymethyl-dihydro-furan-2-one

: 76236-33-4
(3S,4S)-(+)-3-(2-(3,4,5-trimethoxyphenyl)-1,3-dithiane-2-yl)-4-trityloxymethyl-butan-4-olide

Guidance literature:: Multi-step reaction with 2 steps

1: NaIO₄ / 18-crown-6 / ethyl acetate; H₂O / 50 °C

2: lithiation, THF, -78 degC

With sodium periodate; 18-crown-6 ether; In water; ethyl acetate;
DOI:10.1016/0040-4039(80)88012-9