rac-3-benzyloxy-17-methyl-morphinane

Base Information

• Chemical Name: rac-3-benzyloxy-17-methyl-morphinane
• CAS No.: 98985-27-4
• Molecular Formula: C₂₄H₂₉NO
• Molecular Weight: 347.5
• Mol file: 98985-27-4.mol

Synonyms:

Chemical Property of rac-3-benzyloxy-17-methyl-morphinane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-3-benzyloxy-17-methyl-morphinane

There total 3 articles about rac-3-benzyloxy-17-methyl-morphinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-1-(p-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline (51072-36-7,57849-23-7) → rac-3-benzyloxy-17-methyl-morphinane (98985-27-4,143899-95-0)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol; water / Nachfolgenden Hydrieren an Raney-Nickel

2: phosphoric acid

With methanol; phosphoric acid; water;

DOI:10.1002/hlca.19500330606

Reference yield:

1-(p-methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline (38969-65-2,31414-58-1) → rac-3-benzyloxy-17-methyl-morphinane (98985-27-4,143899-95-0)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphoric acid

With phosphoric acid;

DOI:10.1002/hlca.19500330606

Reference yield:

racemorphan (77-07-6,125-73-5,297-90-5,2616-02-6,59684-82-1) → rac-3-benzyloxy-17-methyl-morphinane (98985-27-4,143899-95-0)

Guidance literature:

DOI:10.1002/hlca.19500330606

upstream raw materials:

racemorphan

(+)-1-(p-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline

1-(p-methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline