(E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime

Base Information

• Chemical Name: (E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime
• CAS No.: 230311-05-4
• Molecular Formula: C₁₆H₁₉NO₂
• Molecular Weight: 257.332
• Mol file: 230311-05-4.mol

Synonyms:

Chemical Property of (E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime

There total 1 articles about (E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Methylfurfural (620-02-0) + (R)-(+)-N-(1-phenylbutoxy)phthalimide (197709-54-9) → (Z)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime + (E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime (230311-05-4)

Guidance literature:

With hydrazine hydrate; Yield given; Multistep reaction. Yields of byproduct given; 1.) EtOH, heating, 2.) room temperature, overnight;

DOI:10.1021/jo9901079

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + (E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime (230311-05-4) → (1S,1'R)-N-(1-phenylbutoxy)-5-(2-methylfuryl)-1-pentylamine + (1R,1'R)-(+)-N-(1-phenylbutoxy)-5-(2-methylfuryl)-1-pentylamine

Guidance literature:

With boron trifluoride diethyl etherate; Yield given; Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) toluene, -78 deg C, 15 min, 2.) 30 min;

DOI:10.1021/jo9901079

Reference yield:

methyllithium (917-54-4) + (E)-(R)-(+)-O-(1-phenylbutyl)-5-methyl-2-furaldoxime (230311-05-4) → (1S,1'R)-N-(1-phenylbutoxy)-5-(2-methylfuryl)-1-ethylamine + (1R,1'R)-(+)-N-(1-phenylbutoxy)-5-(2-methylfuryl)-1-ethylamine

Guidance literature:

With boron trifluoride diethyl etherate; Yield given; Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) toluene, -78 deg C, 15 min, 2.) 30 min;

DOI:10.1021/jo9901079

upstream raw materials:

5-Methylfurfural

(R)-(+)-N-(1-phenylbutoxy)phthalimide

Refernces