Boc-ser-nhch2c6h5

Base Information

Chemical Name:Boc-ser-nhch2c6h5
CAS No.:141108-78-3
Molecular Formula:C15H22N2O4
Molecular Weight:294.351
Hs Code.:
European Community (EC) Number:689-217-5
Mol file:141108-78-3.mol

Synonyms:141108-78-3;Boc-ser-nhch2c6h5;SCHEMBL9582823;tert-Butyl (S)-(1-(benzylamino)-3-hydroxy-1-oxopropan-2-yl)carbamate

Suppliers and Price of Boc-ser-nhch2c6h5

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Boc-ser-nhch2c6h5

Chemical Property:

PSA：87.66000
LogP:1.97020
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:294.15795719
Heavy Atom Count:21
Complexity:346

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CO)C(=O)NCC1=CC=CC=C1
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CO)C(=O)NCC1=CC=CC=C1
Uses Boc-D-Serine Benzylamide is an intermediate for the preparation of lacosamide from enantiomerically pure D-serine derivative.

Technology Process of Boc-ser-nhch2c6h5

There total 3 articles about Boc-ser-nhch2c6h5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 3262-72-4
(S)-N-(tert-butoxycarbonyl)serine

: 100-46-9
benzylamine

: 141108-78-3
tert-butyl (S)-(1-(benzylamino)-3-hydroxy-1-oxopropan-2-yl)carbamate

Guidance literature:: With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; at 20 ℃; for 4h;

Reference yield:

: 3262-72-4
(S)-N-(tert-butoxycarbonyl)serine

: 141108-78-3
tert-butyl (S)-(1-(benzylamino)-3-hydroxy-1-oxopropan-2-yl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: NMM / tetrahydrofuran

2: NMM / tetrahydrofuran / 2 h

With 4-methyl-morpholine; In tetrahydrofuran;