4-BROMO-TOLUENE-3-SULFONYL CHLORIDE

Base Information

• Chemical Name: 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE
• CAS No.: 141113-98-6
• Molecular Formula: C7H6BrClO2S
• Molecular Weight: 269.546
• Hs Code.: 2904990090
• Mol file: 141113-98-6.mol

Synonyms:4-Bromtoluol-3-sulfonchlorid;4-Brom-toluol-3-sulfonylchlorid;2-Bromo-5-methylbenzene-1-sulfonyl chloride;4-bromo-toluene-3-sulfonyl chloride;2-Bromo-5-methyl-benzenesulfonyl chloride;

Chemical Property of 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE

Chemical Property:

• PSA: 42.52000
• LogP: 3.76580
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

4-Bromo-toluene-3-sulfonicacidsodiumsalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE

There total 5 articles about 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

para-bromotoluene (106-38-7) → 2-bromo-5-methylbenzenesulfonyl chloride (141113-98-6) + 5-bromo-2-methyl-benzene-sulfonyl chloride (69321-56-8)

Guidance literature:

With chlorosulfonic acid; In dichloromethane;

DOI:10.1016/j.bmc.2019.115231

Reference yield:

4-bromo-toluene-3-sulfonic acid (56919-22-3) → 2-bromo-5-methylbenzenesulfonyl chloride (141113-98-6)

Guidance literature:

With phosphorus pentachloride; In toluene;

Reference yield:

para-bromotoluene (106-38-7) → 2-bromo-5-methylbenzenesulfonyl chloride (141113-98-6)

Guidance literature:

With chlorosulfonic acid; at -10 - 0 ℃; for 0.5h;

upstream raw materials:

para-bromotoluene

4-bromo-toluene-3-sulfonic acid

Downstream raw materials:

1-bromo-2-methanesulfonyl-4-methylbenzene

1-bromo-4-(bromomethyl)-2-(methylsulfonyl)benzene

Refernces

• 1、 -. "Biphenylsulfonyl-substituted imidazole derivatives, their preparation process, their use as a drug or diagnostic agent and drug containing them". Page column 18. . Retrieved 2008/06/13.
• 2、 -. "Perfluoroalkyl-substituted, benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament containing them". . . Retrieved 2008/06/13.