N'-(2-furylmethylene)-2-[(4-methoxyphenyl)amino]acetohydrazide

Base Information

• Chemical Name: N'-(2-furylmethylene)-2-[(4-methoxyphenyl)amino]acetohydrazide
• CAS No.: 303083-30-9
• Molecular Formula: C₁₄H₁₅N₃O₃
• Molecular Weight: 273.291
• European Community (EC) Number: 659-869-5
• Mol file: 303083-30-9.mol

Synonyms:N'-(2-furylmethylene)-2-[(4-methoxyphenyl)amino]acetohydrazide;N'-(Furan-2-ylmethylene)-2-((4-methoxyphenyl)amino)acetohydrazide;303083-30-9;AKOS003411512;N'-[(E)-2-furylmethylidene]-2-(4-methoxyanilino)acetohydrazide

Chemical Property of N'-(2-furylmethylene)-2-[(4-methoxyphenyl)amino]acetohydrazide

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 273.11134135
• Heavy Atom Count: 20
• Complexity: 328

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)NCC(=O)NN=CC2=CC=CO2
• Isomeric SMILES: COC1=CC=C(C=C1)NCC(=O)N/N=C/C2=CC=CO2

Technology Process of N'-(2-furylmethylene)-2-[(4-methoxyphenyl)amino]acetohydrazide

There total 1 articles about N'-(2-furylmethylene)-2-[(4-methoxyphenyl)amino]acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

furfural (98-01-1) + 2-((4-methoxyphenyl)amino)acetohydrazide (79476-73-6) → 2-(4-methoxyphenylamino)-N'-(furan-2-yl-methylene)acetohydrazide (303083-30-9)

Guidance literature:

at 60 ℃; for 4h;

DOI:10.1016/j.saa.2008.09.015

Reference yield:

2-(4-methoxyphenylamino)-N'-(furan-2-yl-methylene)acetohydrazide (303083-30-9) + hafnium tetrachloride (13499-05-3) → HfCl4(N'-(furan-2-ylmethylene)-2-(4-methoxyphenylamino)acetohydrazide) (1130231-25-2)

Guidance literature:

In ethanol; hot EtOH soln. of ligand added to HfCl4, heated at 80°C for 3 h with stirring; filtered, washed with EtOH, dried under vac. over CaCl2; elem. anal.;

DOI:10.1016/j.saa.2008.09.015

Reference yield:

zinc(II) nitrate (10196-18-6) + 2-(4-methoxyphenylamino)-N'-(furan-2-yl-methylene)acetohydrazide (303083-30-9) → Zn(NO3)2(N'-(furan-2-ylmethylene)-2-(4-methoxyphenylamino)acetohydrazide)2*H2O (1130231-23-0)

Guidance literature:

In ethanol; hot EtOH soln. of ligand added to Zn(NO3)2, heated at 80°C for 3 h with stirring; filtered, washed with EtOH, dried under vac. over CaCl2; elem. anal.;

DOI:10.1016/j.saa.2008.09.015

upstream raw materials:

furfural

2-((4-methoxyphenyl)amino)acetohydrazide

Downstream raw materials:

Co(NO₃)2(N'-(furan-2-ylmethylene)-2-(4-methoxyphenylamino)acetohydrazide)2

Ni(OAc)2(H₂O)(N'-(furan-2-ylmethylene)-2-(4-methoxyphenylamino)acetohydrazide)*H₂O

Cu(OAc)(H₂O)(N'-(furan-2-ylmethylene)-2-(4-methoxyphenylamino)acetohydrazide^(1-))*H₂O

HfCl₄(N'-(furan-2-ylmethylene)-2-(4-methoxyphenylamino)acetohydrazide)