3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid

Base Information

• Chemical Name: 3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid
• CAS No.: 1254329-57-1
• Molecular Formula: C₃₅H₃₁N₅O₅S
• Molecular Weight: 633.728
• Mol file: 1254329-57-1.mol

Synonyms:

Chemical Property of 3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid

There total 3 articles about 3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

1,3-propanesultone (1120-71-4) + 6-amino-1-pyridin-2-yl-3,4-bis(p-tolylamino)-benzo[g]isoquinoline-5,10-dione (1254329-49-1) → 3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid (1254329-57-1)

Guidance literature:

In toluene; for 20h; Reflux;

DOI:10.1515/znb-2010-0709

Reference yield:

5-aminonaphthalene-1,4-dione (63038-00-6) → 3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid (1254329-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / Reflux

2: toluene / 20 h / Reflux

In dichloromethane; toluene;

DOI:10.1515/znb-2010-0709

Reference yield:

p-Tolyl-{4-[(E)-p-tolylimino]-4H-pyrido[1,2-a]pyrazin-3-yl}-amine → 3-(5,10-dioxo-1-(pyridin-2-yl)-3,4-bis(p-tolylamino)-5,10-dihydrobenzo[g]isoquinolin-6-ylamino)propane-1-sulfonic acid (1254329-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / Reflux

2: toluene / 20 h / Reflux

In dichloromethane; toluene;

DOI:10.1515/znb-2010-0709

upstream raw materials:

1,3-propanesultone

6-amino-1-pyridin-2-yl-3,4-bis(p-tolylamino)-benzo[g]isoquinoline-5,10-dione

5-aminonaphthalene-1,4-dione