tetrabutylammonium (E)-2-(p-chlorophenyl)vinylsulphonate

Base Information

• Chemical Name: tetrabutylammonium (E)-2-(p-chlorophenyl)vinylsulphonate
• CAS No.: 110679-88-4
• Molecular Formula: C₈H₆ClO₃S*C₁₆H₃₆N
• Molecular Weight: 460.121
• Mol file: 110679-88-4.mol

Synonyms:

Chemical Property of tetrabutylammonium (E)-2-(p-chlorophenyl)vinylsulphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tetrabutylammonium (E)-2-(p-chlorophenyl)vinylsulphonate

There total 2 articles about tetrabutylammonium (E)-2-(p-chlorophenyl)vinylsulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetra(n-butyl)ammonium hydrogensulfate (32503-27-8) + 4-chlorobenzaldehyde (104-88-1) + lithium diethylphosphoryl methanesulfonate (110679-80-6) → tetrabutylammonium (Z)-2-(p-chlorophenyl)vinylsulphonate (110680-00-7) + tetrabutylammonium (E)-2-(p-chlorophenyl)vinylsulphonate (110679-88-4)

Guidance literature:

With lithium hydroxide; n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, -40 deg C then -15 deg C for 60 min 2.) -78 deg C for 30 min then stirring overnight at room temp. 3.) H₂O, room temperature;

DOI:10.1016/S0040-4039(00)95921-5

Reference yield:

4-chlorobenzaldehyde (104-88-1) + tetrabutylammonium diethylphosphorylmethanesulphonate (114086-65-6) → tetrabutylammonium (Z)-2-(p-chlorophenyl)vinylsulphonate (110680-00-7) + tetrabutylammonium (E)-2-(p-chlorophenyl)vinylsulphonate (110679-88-4)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1) THF, -78 deg C, 20 min, 2) THF, -78 deg C, 30 min then RT, 18 h;

DOI:10.1016/S0040-4020(01)87688-2

upstream raw materials:

tetra(n-butyl)ammonium hydrogensulfate

4-chlorobenzaldehyde

lithium diethylphosphoryl methanesulfonate

tetrabutylammonium diethylphosphorylmethanesulphonate

Refernces

• 1、 Carretero, Juan Carlos,Demillequand, Marc,Ghosez, Leon. "SYNTHESIS OF α,β-UNSATURATED SULPHONATES VIA THE WITTIG-HORNER REACTION". . p. 5125 - 5134. Retrieved 2007/10/02.