2-(4-Methylphenyl)-4H-pyrazolo[1,5-A]indole

Base Information

Chemical Name:2-(4-Methylphenyl)-4H-pyrazolo[1,5-A]indole
CAS No.:141235-71-4
Molecular Formula:C17H14N2
Molecular Weight:246.312
Hs Code.:
DSSTox Substance ID:DTXSID70569230
Wikidata:Q82456336

Synonyms:141235-71-4;2-(p-tolyl)-4H-pyrazolo[1,5-a]indole;2-(4-METHYLPHENYL)-4H-PYRAZOLO[1,5-A]INDOLE;DTXSID70569230

Suppliers and Price of 2-(4-Methylphenyl)-4H-pyrazolo[1,5-A]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-(4-Methylphenyl)-4H-pyrazolo[1,5-A]indole

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:246.115698455
Heavy Atom Count:19
Complexity:321

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NN3C(=C2)CC4=CC=CC=C43

Technology Process of 2-(4-Methylphenyl)-4H-pyrazolo[1,5-A]indole

There total 3 articles about 2-(4-Methylphenyl)-4H-pyrazolo[1,5-A]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 141235-84-9
2-formyl-1-(4-methylbenzylideneamino)indoline

: 141235-71-4
2-(4-methylphenyl)-4H-pyrazolo<1,5-a>indole

Guidance literature:: With 1,2-dimethoxyethane; NbCl₃; In tetrahydrofuran; for 1h; Heating;
DOI:10.1246/cl.1992.451

Reference yield:

: 104-87-0
4-methyl-benzaldehyde

: 141235-71-4
2-(4-methylphenyl)-4H-pyrazolo<1,5-a>indole

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / 60percent aq. AcOH / Ambient temperature

2: 81 percent / DMSO, oxalyl chloride, Et₃N / CH₂Cl₂ / 0.83 h / -60 °C

3: 69 percent / NbCl₃*DME / tetrahydrofuran / 1.5 h / Heating

With 1,2-dimethoxyethane; oxalyl dichloride; NbCl₃; acetic acid; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane;

Reference yield:

: 153705-25-0
2-hydroxymethyl-1-(4-methylbenzylideneamino)indoline

: 141235-71-4
2-(4-methylphenyl)-4H-pyrazolo<1,5-a>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / DMSO, oxalyl chloride, Et₃N / CH₂Cl₂ / 0.83 h / -60 °C

2: 69 percent / NbCl₃*DME / tetrahydrofuran / 1.5 h / Heating

With 1,2-dimethoxyethane; oxalyl dichloride; NbCl₃; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane;