(5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester

Base Information

• Chemical Name: (5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester
• CAS No.: 117333-08-1
• Molecular Formula: C₃₀H₄₁NO₄
• Molecular Weight: 479.66
• Mol file: 117333-08-1.mol

Synonyms:

Chemical Property of (5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester

There total 2 articles about (5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-(8R,5Z,9E,11Z,14Z,17Z)-8-hydroxy-5,9,11,14,17-isosapentaenoic acid (117407-06-4) → (5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester (117333-08-1)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: toluene / 13 h / 90 °C

In diethyl ether; toluene;

DOI:10.1002/hlca.19880710523

Reference yield:

(+)-(8R,5Z,9E,11Z,14Z,17Z)-ethyl 8-hydroxy-5,9,11,14,17-isosapentaenoic acid → (5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester (117333-08-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / methanol / 0.17 h / Ambient temperature

2: toluene / 13 h / 90 °C

In methanol; toluene;

DOI:10.1002/hlca.19880710523

Reference yield:

(5Z,9E,11Z,14Z,17Z)-(R)-8-((S)-1-Phenyl-ethylcarbamoyloxy)-icosa-5,9,11,14,17-pentaenoic acid methyl ester (117333-08-1) → (-)-(2R)-dimethyl <(S)-(1-phenylethyl)carbamoyloxy>butanedioate

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1002/hlca.19880710523

upstream raw materials:

(+)-(8R,5Z,9E,11Z,14Z,17Z)-8-hydroxy-5,9,11,14,17-isosapentaenoic acid

Refernces