Methyl 3-(acetyloxy)-4-carbamoylcyclopentanecarboxylate

Base Information

Chemical Name:Methyl 3-(acetyloxy)-4-carbamoylcyclopentanecarboxylate
CAS No.:23722-86-3
Molecular Formula:C₁₀H₁₅NO₅
Molecular Weight:229.233
Hs Code.:
NSC Number:133717
DSSTox Substance ID:DTXSID30299925
Mol file:23722-86-3.mol

Synonyms:23722-86-3;methyl 3-(acetyloxy)-4-carbamoylcyclopentanecarboxylate;NSC133717;DTXSID30299925;NSC-133717

Suppliers and Price of Methyl 3-(acetyloxy)-4-carbamoylcyclopentanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 3-(acetyloxy)-4-carbamoylcyclopentanecarboxylate

Chemical Property:

Vapor Pressure:5.59E-06mmHg at 25°C
Boiling Point:380.1°C at 760 mmHg
Flash Point:188.8°C
Density:1.24g/cm³
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:229.09502258
Heavy Atom Count:16
Complexity:314

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1CC(CC1C(=O)N)C(=O)OC

Technology Process of Methyl 3-(acetyloxy)-4-carbamoylcyclopentanecarboxylate

There total 5 articles about Methyl 3-(acetyloxy)-4-carbamoylcyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68715-63-9,99295-46-2
(1R,3R,4S)-3-Acetoxy-4-chlorocarbonyl-cyclopentanecarboxylic acid methyl ester

: 23722-86-3,99295-44-0
(+/-)-methyl (1β,3β,4β)-3-acetoxy-4-carbamoylcyclopentanecarboxylate

Guidance literature:: With ammonia; In benzene; for 0.5h; Yield given;
DOI:10.1139/v85-464

Reference yield:

: 68715-61-7,99295-45-1
(1R*,3R*,4R*)-methyl 4-acetyloxy-3-carboxycyclopentane-1-carboxylate

: 23722-86-3,99295-44-0
(+/-)-methyl (1β,3β,4β)-3-acetoxy-4-carbamoylcyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) SOCl₂, pyridine, 2.) SOCl₂, pyridine, N,N-dimethylformamide / 1.) benzene, 2.) benzene, 2 h, reflux, RT, overnight

2: NH₃ (gaseous) / benzene / 0.5 h

With pyridine; thionyl chloride; ammonia; N,N-dimethyl-formamide; In benzene;
DOI:10.1139/v85-464

Reference yield:

: 23722-84-1,99236-91-6
(+/-)-(1β,3β,4β)-4-acetoxy-1,3-cyclopentanedicarboxylic acid anhydride

: 23722-86-3,99295-44-0
(+/-)-methyl (1β,3β,4β)-3-acetoxy-4-carbamoylcyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 22 h / Ambient temperature

2: 1.) SOCl₂, pyridine, 2.) SOCl₂, pyridine, N,N-dimethylformamide / 1.) benzene, 2.) benzene, 2 h, reflux, RT, overnight

3: NH₃ (gaseous) / benzene / 0.5 h

With pyridine; thionyl chloride; ammonia; N,N-dimethyl-formamide; In benzene;
DOI:10.1139/v85-464