3-(2-Fluorobenzyl)quinazolin-4(3H)-one

Base Information

Chemical Name:3-(2-Fluorobenzyl)quinazolin-4(3H)-one
CAS No.:141305-95-5
Molecular Formula:C15H11FN2O
Molecular Weight:254.25900
Hs Code.:
European Community (EC) Number:658-486-0
Nikkaji Number:J476.013A

Synonyms:3-(2-Fluorobenzyl)quinazolin-4(3H)-one;141305-95-5;Oprea1_616993;4(3h)-quinazolinone,3-[(2-fluorophenyl)methyl]-;3-[(2-fluorophenyl)methyl]-3,4-dihydroquinazolin-4-one;AKOS001137314;CCG-307207;3-(2-FLUOROBENZYL)-4(3H)-QUINAZOLINONE;SR-01000459525;SR-01000459525-1;Z91652473

Suppliers and Price of 3-(2-Fluorobenzyl)quinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-(2-Fluorobenzyl)quinazolin-4(3H)-one

Chemical Property:

PSA：34.89000
LogP:2.58390
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:254.08554114
Heavy Atom Count:19
Complexity:371

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CN2C=NC3=CC=CC=C3C2=O)F

Technology Process of 3-(2-Fluorobenzyl)quinazolin-4(3H)-one

There total 3 articles about 3-(2-Fluorobenzyl)quinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 89-99-6
2-fluorobenzylamine

: 360795-67-1
ethyl 2-isocyanobenzoate

: 141305-95-5
3-(2-Fluoro-benzyl)-3H-quinazolin-4-one

Guidance literature:: With iron(II,III) oxide; caesium carbonate; palladium; In 1,4-dioxane; at 20 ℃; for 24h;
DOI:10.1039/c5cy01973g

Reference yield:

: 118-48-9
isatoic anhydride

: 141305-95-5
3-(2-Fluoro-benzyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / ethanol / 2 h / Ambient temperature

2: 63 percent / 2 h / Heating

In ethanol;

Reference yield:

: 89-99-6
2-fluorobenzylamine

: 141305-95-5
3-(2-Fluoro-benzyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / ethanol / 2 h / Ambient temperature

2: 63 percent / 2 h / Heating

In ethanol;