(R)-diethyl 2-(1-(2,4-dimethoxyphenyl)-3-oxopropan-2-yl)malonate

Base Information

Chemical Name:(R)-diethyl 2-(1-(2,4-dimethoxyphenyl)-3-oxopropan-2-yl)malonate
CAS No.:1374250-38-0
Molecular Formula:C₁₈H₂₄O₇
Molecular Weight:352.384
Hs Code.:

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Chemical Property of (R)-diethyl 2-(1-(2,4-dimethoxyphenyl)-3-oxopropan-2-yl)malonate

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Technology Process of (R)-diethyl 2-(1-(2,4-dimethoxyphenyl)-3-oxopropan-2-yl)malonate

There total 1 articles about (R)-diethyl 2-(1-(2,4-dimethoxyphenyl)-3-oxopropan-2-yl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 685-87-0
Diethyl 2-bromomalonate

: 848081-07-2
3-(2',4'-dimethoxyphenyl)propionaldehyde

: 1374250-38-0
(R)-diethyl 2-(1-(2,4-dimethoxyphenyl)-3-oxopropan-2-yl)malonate

: (S)-diethyl 2-(1-(2,4-dimethoxyphenyl)-3-oxopropan-2-yl)malonate

Guidance literature:: Diethyl 2-bromomalonate; With (2R,5S)-2-tert-butyl-3,5-dimethylimidazolidin-4-one trifluoromethanesulfonate; rose bengal; lithium chloride; In N,N-dimethyl-formamide; Inert atmosphere;

3-(2',4'-dimethoxyphenyl)propionaldehyde; With 2,6-dimethylpyridine; In N,N-dimethyl-formamide; for 4h; optical yield given as %ee; enantioselective reaction; Inert atmosphere; UV-irradiation;
DOI:10.1039/c2gc35118h