(3S)--3-aminopiperidine

Base Information

• Chemical Name: (3S)--3-aminopiperidine
• CAS No.: 80918-64-5
• Molecular Formula: C₂₉H₃₀N₂P₂
• Molecular Weight: 468.518
• Mol file: 80918-64-5.mol

Synonyms:

Chemical Property of (3S)--3-aminopiperidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S)--3-aminopiperidine

There total 3 articles about (3S)--3-aminopiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-ornithine hydrochloride (3184-13-2,36630-89-4) → (3S)--3-aminopiperidine (80918-64-5)

Guidance literature:

Multi-step reaction with 4 steps

2: 1.) sodium methylate, 2.) hydrochloric acid

3: lithium aluminum hydride

4: triethylamine

With hydrogenchloride; lithium aluminium tetrahydride; sodium methylate; triethylamine;

DOI:10.1246/cl.1981.1691

Reference yield:

methyl (S)-2,5-diaminopentanoate dihydrochloride (40216-82-8,60080-69-5) → (3S)--3-aminopiperidine (80918-64-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) sodium methylate, 2.) hydrochloric acid

2: lithium aluminum hydride

3: triethylamine

With hydrogenchloride; lithium aluminium tetrahydride; sodium methylate; triethylamine;

DOI:10.1246/cl.1981.1691

Reference yield:

(S)-piperidin-3-amine (54012-73-6,80918-66-7,127294-73-9,128441-15-6) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → (3S)--3-aminopiperidine (80918-64-5)

Guidance literature:

With triethylamine;

DOI:10.1246/cl.1981.1691

upstream raw materials:

(S)-piperidin-3-amine

chloro-diphenylphosphine

L-ornithine hydrochloride

methyl (S)-2,5-diaminopentanoate dihydrochloride