1-<(1'S,2'R,3'S,4'S)-1'-((tert-butyldimethylsilyl)oxy)-3'-(phenylsulfonyl)-4'-methylcyclopent-2'-yl>-1-<(1R,6S)-7,7-dimethylbicyclo<4.1.0>hept-2-en-3-yl>-acetonitryle

Base Information

• Chemical Name: 1-<(1'S,2'R,3'S,4'S)-1'-((tert-butyldimethylsilyl)oxy)-3'-(phenylsulfonyl)-4'-methylcyclopent-2'-yl>-1-<(1R,6S)-7,7-dimethylbicyclo<4.1.0>hept-2-en-3-yl>-acetonitryle
• CAS No.: 106051-67-6
• Molecular Formula: C₂₉H₄₃NO₃SSi
• Molecular Weight: 513.817
• Mol file: 106051-67-6.mol

Synonyms:

Chemical Property of 1-<(1'S,2'R,3'S,4'S)-1'-((tert-butyldimethylsilyl)oxy)-3'-(phenylsulfonyl)-4'-methylcyclopent-2'-yl>-1-<(1R,6S)-7,7-dimethylbicyclo<4.1.0>hept-2-en-3-yl>-acetonitryle

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-<(1'S,2'R,3'S,4'S)-1'-((tert-butyldimethylsilyl)oxy)-3'-(phenylsulfonyl)-4'-methylcyclopent-2'-yl>-1-<(1R,6S)-7,7-dimethylbicyclo<4.1.0>hept-2-en-3-yl>-acetonitryle

There total 1 articles about 1-<(1'S,2'R,3'S,4'S)-1'-((tert-butyldimethylsilyl)oxy)-3'-(phenylsulfonyl)-4'-methylcyclopent-2'-yl>-1-<(1R,6S)-7,7-dimethylbicyclo<4.1.0>hept-2-en-3-yl>-acetonitryle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R,6S)-7,7-dimethyl-3-acetonitrilebicyclo<4.1.0>hept-2-ene (101245-15-2) + ((1S,4S)-3-Benzenesulfonyl-4-methyl-cyclopent-2-enyloxy)-tert-butyl-dimethyl-silane (115047-47-7) → (1R,6S)-2-<(1'S,2'R,3'R,4'S)-1'-((tert-butyldimethylsilil)oxy)-3'-(phenylsulfonyl)-4'-methylcyclopent-2'-yl>-3-(cyanoethyl)-7,7-dimethylbicyclo<4.1.0>hept-3-ene (115047-48-8) + 1-<(1'S,2'R,3'S,4'S)-1'-((tert-butyldimethylsilyl)oxy)-3'-(phenylsulfonyl)-4'-methylcyclopent-2'-yl>-1-<(1R,6S)-7,7-dimethylbicyclo<4.1.0>hept-2-en-3-yl>-acetonitryle (106051-67-6,115115-26-9,115115-27-0)

Guidance literature:

With n-butyllithium; potassium tert-butylate; diisopropylamine; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, -78 deg C, 1 h, 2.) 10 min;

DOI:10.1021/jo00251a001

upstream raw materials:

(1R,6S)-7,7-dimethyl-3-acetonitrilebicyclo<4.1.0>hept-2-ene

((1S,4S)-3-Benzenesulfonyl-4-methyl-cyclopent-2-enyloxy)-tert-butyl-dimethyl-silane