(3-(Benzyloxy)cyclobutyl)methanol

Base Information

Chemical Name:(3-(Benzyloxy)cyclobutyl)methanol
CAS No.:141352-64-9
Molecular Formula:C12H16O2
Molecular Weight:192.258
Hs Code.:
European Community (EC) Number:878-175-5
DSSTox Substance ID:DTXSID501276479
Mol file:141352-64-9.mol

Synonyms:141352-64-9;[cis-3-(Benzyloxy)cyclobutyl]methanol;[trans-3-(Benzyloxy)cyclobutyl]methanol;128041-57-6;(3-(benzyloxy)cyclobutyl)methanol;[3-(benzyloxy)cyclobutyl]methanol;156865-32-6;(3-phenylmethoxycyclobutyl)methanol;(trans-3-(Benzyloxy)cyclobutyl)methanol;(cis-3-(Benzyloxy)cyclobutyl)methanol;3-(Phenylmethoxy)cyclobutanemethanol;SCHEMBL583269;SCHEMBL8345375;SCHEMBL8348108;cis-3-Benzyloxycyclobutylmethanol;GUMINBOCIUCMJL-UHFFFAOYSA-N;(3-Benzyloxy-cyclobutyl)-methanol;DTXSID501276479;trans-3-Benzyloxycyclobutylmethanol;MFCD28344028;MFCD28344050;AT11874;AT38375;AT38383;cis-3-(Phenylmethoxy)cyclobutanemethanol;BS-40811;BS-40815;CS-0214889;EN300-2012780

Suppliers and Price of (3-(Benzyloxy)cyclobutyl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (3-(Benzyloxy)cyclobutyl)methanol

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:192.115029749
Heavy Atom Count:14
Complexity:158

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC1OCC2=CC=CC=C2)CO

Technology Process of (3-(Benzyloxy)cyclobutyl)methanol

There total 6 articles about (3-(Benzyloxy)cyclobutyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.9%

: 141352-62-7
ethyl 3α-(benzyloxy)cyclobutane-1α-carboxylate

: 141352-64-9
3α-(benzyloxy)cyclobutane-1α-methanol

Guidance literature:: With lithium aluminium tetrahydride; In 1,2-dimethoxyethane; at 85 ℃; for 60h;
DOI:10.1002/hlca.19920750216

Reference yield:

: 54307-67-4
1-bromo-2-benzyloxy-3-chloropropane

: 141352-64-9
3α-(benzyloxy)cyclobutane-1α-methanol

Guidance literature:: Multi-step reaction with 6 steps

2: aq. 4M KOH / H₂O; ethanol / 5 h / Heating

3: 88.6 percent / 215 °C / 0.4 Torr

4: 99.5 percent / oxalyl chloride / CCl₄ / 1) 0 deg C, 1 h, 2) r.t., 12 h

5: CCl₄ / 5 h / Ambient temperature

6: 91.9 percent / LiAlH₄ / 1,2-dimethoxy-ethane / 60 h / 85 °C

With potassium hydroxide; lithium aluminium tetrahydride; oxalyl dichloride; In tetrachloromethane; 1,2-dimethoxyethane; ethanol; water;
DOI:10.1002/hlca.19920750216

Reference yield:

: 54166-15-3
diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate

: 141352-64-9
3α-(benzyloxy)cyclobutane-1α-methanol

Guidance literature:: Multi-step reaction with 5 steps

1: aq. 4M KOH / H₂O; ethanol / 5 h / Heating

2: 88.6 percent / 215 °C / 0.4 Torr

3: 99.5 percent / oxalyl chloride / CCl₄ / 1) 0 deg C, 1 h, 2) r.t., 12 h

4: CCl₄ / 5 h / Ambient temperature

5: 91.9 percent / LiAlH₄ / 1,2-dimethoxy-ethane / 60 h / 85 °C

With potassium hydroxide; lithium aluminium tetrahydride; oxalyl dichloride; In tetrachloromethane; 1,2-dimethoxyethane; ethanol; water;
DOI:10.1002/hlca.19920750216