N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide

Base Information

• Chemical Name: N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide
• CAS No.: 55478-28-9
• Molecular Formula: C₂₂H₂₇N₅O₆
• Molecular Weight: 457.486
• Mol file: 55478-28-9.mol

Synonyms:

Chemical Property of N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide

There total 5 articles about N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine ethyl ester (55478-25-6) → N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide (55478-28-9)

Guidance literature:

With ethanol; hydrazine hydrate;

Reference yield:

(S)-3-benzyloxycarbonylamino-2-oxo-pyrrolidine-1-carboxylic acid benzyl ester (102317-34-0) → N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide (55478-28-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 135 °C

2: ethanol; N₂H₄+H₂O

With ethanol; hydrazine hydrate;

Reference yield:

(S)-2,4-bis-benzyloxycarbonylamino-butyric acid hydrazide → N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine hydrazide (55478-28-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaNO₂; aqueous HCl; acetic acid / Reagens 4: Aether; Behandeln der Reaktionsloesung mit Glycin-aethylester in CHCl₃

2: ethanol; N₂H₄+H₂O

With hydrogenchloride; ethanol; hydrazine hydrate; acetic acid; sodium nitrite;

upstream raw materials:

N-((S)-2,4-bis-benzyloxycarbonylamino-butyryl)-glycine ethyl ester

(S)-3-benzyloxycarbonylamino-2-oxo-pyrrolidine-1-carboxylic acid benzyl ester

(S)-2,4-bis(((benzyloxy)carbonyl)amino)butanoic acid