ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate

Base Information

• Chemical Name: ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate
• CAS No.: 1000981-26-9
• Molecular Formula: C₃₂H₃₆N₂O₇
• Molecular Weight: 560.647
• Mol file: 1000981-26-9.mol

Synonyms:

Chemical Property of ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate

There total 2 articles about ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2E,4R,5S)-5-[(2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino]-4-hydroxy-7-phenyl-hept-2-enoic acid ethyl ester (1092555-17-3) → ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate (1000981-26-9) + ethyl (2R,3S)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate

Guidance literature:

With TBPLi;

DOI:10.1016/j.bmcl.2007.10.056

Reference yield:

→ ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate (1000981-26-9)

Guidance literature:

Reference yield:

ethyl (2S,3R)-3-[(1S,2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenyl-1-hydroxybutyl]oxirane-2-carboxylate (1000981-26-9) → ethyl (2S,3S)-3-[(2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenylbutyryl]oxirane-2-carboxylate (1000981-15-6)

Guidance literature:

With Dess-Martin periodane;

DOI:10.1016/j.bmcl.2007.10.056

upstream raw materials:

(2E,4R,5S)-5-[(2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino]-4-hydroxy-7-phenyl-hept-2-enoic acid ethyl ester

Downstream raw materials:

ethyl (2S,3S)-3-[(2S)-2-((2S)-2-benzyloxycarbonylamino-3-phenylpropionylamino)-4-phenylbutyryl]oxirane-2-carboxylate