2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide

Base Information

• Chemical Name: 2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide
• CAS No.: 712267-69-1
• Molecular Formula: C₂₇H₂₆N₈O₄S
• Molecular Weight: 558.621

Synonyms:

Chemical Property of 2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide

There total 1 articles about 2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-[2-(4-methoxybenzyl)-2H-1,2,3,4-tetrazol-5-yl]acetate (91660-72-9) + N-(4-tert-butyl-1,3-thiazol-2-yl)-3-formyl-2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxamide (475062-18-1) → 2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide (712267-69-1)

Guidance literature:

With piperidine; pyridine;

DOI:10.1016/j.bmcl.2004.03.007

Reference yield:

2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide (712267-69-1) → trichloroacetyl-carbamic acid 1-(8-(4-tert-butyl-thiazol-2-ylcarbamoyl)-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)-piperidin-3-yl ester

Guidance literature:

Multi-step reaction with 3 steps

1: iPr₂NEt

With N-ethyl-N,N-diisopropylamine;

DOI:10.1016/j.bmcl.2004.03.007

Reference yield:

2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide (712267-69-1) → 2-(3-hydroxy-piperidin-1-yl)-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide (475062-21-6)

Guidance literature:

Multi-step reaction with 2 steps

1: iPr₂NEt

With N-ethyl-N,N-diisopropylamine;

DOI:10.1016/j.bmcl.2004.03.007

upstream raw materials:

ethyl 2-[2-(4-methoxybenzyl)-2H-1,2,3,4-tetrazol-5-yl]acetate

N-(4-tert-butyl-1,3-thiazol-2-yl)-3-formyl-2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxamide

Downstream raw materials:

2-(3-hydroxy-piperidin-1-yl)-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide

carbamic acid 1-(8-(4-tert-butyl-thiazol-2-ylcarbamoyl)-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)-piperidin-3-yl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 712267-69-1 2-hydroxy-3-{2-[2-(4-methoxy-benzyl)-2H-tetrazol-5-yl]-vinyl}-4-oxo-4H-pyrido[1,2-a]pyrimidine-8-carboxylic acid (4-tert-butyl-thiazol-2-yl)-amide

Send

Send

Metric Ton KG G Pound L ML

Send

Send