(2-ethyl-3-methoxy-phenyl)-acetonitrile

Base Information

• Chemical Name: (2-ethyl-3-methoxy-phenyl)-acetonitrile
• CAS No.: 855926-63-5
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.23
• Mol file: 855926-63-5.mol

Synonyms:

Chemical Property of (2-ethyl-3-methoxy-phenyl)-acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-ethyl-3-methoxy-phenyl)-acetonitrile

There total 5 articles about (2-ethyl-3-methoxy-phenyl)-acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-ethyl-3-methoxy-phenyl)-acetic acid amide (861057-34-3) → (2-ethyl-3-methoxy-phenyl)-acetonitrile (855926-63-5)

Guidance literature:

With phosphorus pentachloride;

Reference yield:

2-Ethyl-3-Methoxybenzoic Acid (57598-51-3) → (2-ethyl-3-methoxy-phenyl)-acetonitrile (855926-63-5)

Guidance literature:

Multi-step reaction with 5 steps

1: thionyl chloride

2: diazomethane; diethyl ether / Erwaermen einer Loesung des Reaktionsprodukts in Dioxan mit einem Gemisch von Silberoxid, Natriumthiosulfat und Natriumcarbonat in Wasser

3: thionyl chloride

4: aqueous ammonia

5: phosphorus (V)-chloride

With diazomethane; ammonium hydroxide; thionyl chloride; diethyl ether; phosphorus pentachloride;

Reference yield:

(2-ethyl-3-methoxy-phenyl)-acetyl chloride (857570-92-4) → (2-ethyl-3-methoxy-phenyl)-acetonitrile (855926-63-5)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous ammonia

2: phosphorus (V)-chloride

With ammonium hydroxide; phosphorus pentachloride;

upstream raw materials:

(2-ethyl-3-methoxy-phenyl)-acetic acid amide

2-Ethyl-3-Methoxybenzoic Acid

(2-ethyl-3-methoxy-phenyl)-acetyl chloride

2-ethyl-3-methoxybenzoyl chloride