4-(4-Hydroxyphenyl)-4-piperidinol

Base Information

Chemical Name:4-(4-Hydroxyphenyl)-4-piperidinol
CAS No.:142001-84-1
Molecular Formula:C11H15NO2
Molecular Weight:193.246
Hs Code.:
DSSTox Substance ID:DTXSID90453824
Wikidata:Q82275080

Synonyms:4-(4-HYDROXYPHENYL)-4-PIPERIDINOL;142001-84-1;4-(4-hydroxyphenyl)piperidin-4-ol;SCHEMBL652586;DTXSID90453824;ZIYRFSOIBBGGDC-UHFFFAOYSA-N;F80311

Suppliers and Price of 4-(4-Hydroxyphenyl)-4-piperidinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(4-Hydroxyphenyl)-4-piperidinol

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:182

Purity/Quality:: 95-99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1(C2=CC=C(C=C2)O)O

Technology Process of 4-(4-Hydroxyphenyl)-4-piperidinol

There total 6 articles about 4-(4-Hydroxyphenyl)-4-piperidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 142001-83-0
1-benzyl-4-(4-benzyloxyphenyl)-4-hydroxypiperidine

: 142001-84-1
4-(4-hydroxyphenyl)-4-hydroxypiperidine

Guidance literature:: With hydrogen; 10percent Pd/C; In ethanol; at 25 ℃; for 62h; under 2585.81 Torr;
DOI:10.1021/jm990428c

Reference yield: 66.6%

: 161609-74-1
1-Benzyloxycarbonyl-4-hydroxy-4-(4-benzyloxyphenyl)-piperidine

: 142001-84-1
4-(4-hydroxyphenyl)-4-hydroxypiperidine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 18 - 25 ℃; for 20h;

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 142001-84-1
4-(4-hydroxyphenyl)-4-hydroxypiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran

2: 46 percent / H₂ / Pd(OH)2 / methanol / 6 h / 20 °C / 3040 Torr

With hydrogen; palladium dihydroxide; In tetrahydrofuran; methanol;
DOI:10.1248/cpb.50.292