7-(p-chlorobenzyl)guanosine hydroiodide

Base Information

• Chemical Name: 7-(p-chlorobenzyl)guanosine hydroiodide
• CAS No.: 88158-05-8
• Molecular Formula: C₁₇H₁₉ClN₅O₅*I
• Molecular Weight: 535.726
• Mol file: 88158-05-8.mol

Synonyms:

Chemical Property of 7-(p-chlorobenzyl)guanosine hydroiodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(p-chlorobenzyl)guanosine hydroiodide

There total 1 articles about 7-(p-chlorobenzyl)guanosine hydroiodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

G (118-00-3) + 1-chloro-4-(iodomethyl)benzene (35424-56-7) → 7-(p-chlorobenzyl)guanosine hydroiodide (88158-05-8)

Guidance literature:

In N,N-dimethyl-formamide; for 24h; Ambient temperature;

DOI:10.1021/jo00176a028

Reference yield:

7-(p-chlorobenzyl)guanosine hydroiodide (88158-05-8) → D-Ribose (32445-75-3) + 2-amino-7-(4-chlorobenzyl)-1H-purin-6(7H)-one

Guidance literature:

With hydrogenchloride; at 50 ℃; Rate constant;

DOI:10.1021/jo00176a028

Reference yield:

7-(p-chlorobenzyl)guanosine hydroiodide (88158-05-8) → 2-Amino-5-(4-chloro-benzylamino)-6-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-ylamino)-pyrimidin-4-ol anion

Guidance literature:

With hydroxide; In methanol; water; at 40 ℃; Rate constant; 0.05 M NaHCO₃-0.05 M Na₂CO₃ buffer, pH 9.9;

DOI:10.1021/jo00176a028

upstream raw materials:

G

1-chloro-4-(iodomethyl)benzene

Downstream raw materials:

D-Ribose