2-Bromo-1,3-cyclopentanedione

Base Information

• Chemical Name: 2-Bromo-1,3-cyclopentanedione
• CAS No.: 14203-24-8
• Molecular Formula: C5H5BrO2
• Molecular Weight: 176.997
• Hs Code.: 2914700090
• Mol file: 14203-24-8.mol

Synonyms:N-bromosuccinimide;2-bromo-1,3-cyclopentadione;1,3-Cyclopentanedione,2-bromo;bromocyclopentanedione;2-Bromo-1,3-cyclopentanedione;2-bromo-cyclopentane-1,3-dione;2-Brom-cyclopentan-1,3-dion;2-bromocyclopentan-1,3-dione;

Chemical Property of 2-Bromo-1,3-cyclopentanedione

Chemical Property:

• Melting Point: 197-199DEoC
• PSA: 34.14000
• LogP: 0.68190

Purity/Quality:

98%Min ^*data from raw suppliers

2-Bromo-1,3-cyclopentanedione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-1,3-cyclopentanedione

There total 3 articles about 2-Bromo-1,3-cyclopentanedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,3-cyclopentadione (3859-41-4) → 2-bromo-cyclopentane-1,3-dione (14203-24-8)

Guidance literature:

With bromine; In acetic acid; at 20 ℃; for 0.75h;

Reference yield:

2-Acetyl-2-brom-cyclopentan-1,3-dion (14203-23-7) → 2-bromo-cyclopentane-1,3-dione (14203-24-8)

Guidance literature:

With sulfuric acid; acetic acid;

Reference yield:

phenyl(tribromomethyl)mercury(II) (3294-60-8) + Dimethyl succinate (106-65-0) → 2-bromo-cyclopentane-1,3-dione (14203-24-8)

Guidance literature:

Multistep reaction; (i) Me₃SiCl, Na, toluene, (ii) /BRN= 3588522/, benzene, (iii) aq. HCl;

upstream raw materials:

1,3-cyclopentadione

2-Acetyl-2-brom-cyclopentan-1,3-dion

phenyl(tribromomethyl)mercury(II)

Dimethyl succinate

Refernces

• 1、 -. "TRICYCLIC MODULATORS OF TNF SIGNALING". Page/Page column 133. . Retrieved 2016/11/02.