2-(2,4-dichlorophenyl)-1H-isoindole-1,3(2H)-dione

Base Information

Chemical Name:2-(2,4-dichlorophenyl)-1H-isoindole-1,3(2H)-dione
CAS No.:80460-33-9
Molecular Formula:C14H7 Cl2 N O2
Molecular Weight:292.121
Hs Code.:
NSC Number:39375
DSSTox Substance ID:DTXSID001001255
Nikkaji Number:J2.338.461B
Wikidata:Q82995118
ChEMBL ID:CHEMBL3094285

Synonyms:80460-33-9;2-(2,4-dichlorophenyl)-1H-isoindole-1,3(2H)-dione;2-(2,4-dichlorophenyl)isoindoline-1,3-dione;NSC39375;Oprea1_473570;Oprea1_562263;CHEMBL3094285;DTXSID001001255;NSC-39375;STK248651;AKOS000749041;SR-01000359470;SR-01000359470-1

Suppliers and Price of 2-(2,4-dichlorophenyl)-1H-isoindole-1,3(2H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(2,4-dichlorophenyl)-1H-isoindole-1,3(2H)-dione

Chemical Property:

Vapor Pressure:1.58E-08mmHg at 25°C
Boiling Point:456.8°C at 760 mmHg
Flash Point:230°C
Density:1.532g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:290.9853839
Heavy Atom Count:19
Complexity:377

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)C3=C(C=C(C=C3)Cl)Cl

Technology Process of 2-(2,4-dichlorophenyl)-1H-isoindole-1,3(2H)-dione

There total 2 articles about 2-(2,4-dichlorophenyl)-1H-isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 85-44-9
phthalic anhydride

: 554-00-7,51908-09-9
2,4-Dichloroaniline

: 80460-33-9
2-(2,4-dichlorophenyl)isoindoline-1,3-dione

Guidance literature:: With acetic acid; for 1.5h; Reflux;
DOI:10.1007/s10870-013-0399-9

Reference yield:

: 80460-33-9
2-(2,4-dichlorophenyl)isoindoline-1,3-dione

Guidance literature:: Phthalsaeure-anhydrid, 2,4-Dichlor-anilin, in sd. Eg., S. 205, 224;

Reference yield: 47.0%

: 80460-33-9
2-(2,4-dichlorophenyl)isoindoline-1,3-dione

: 668987-38-0
5,5-dimethyl-1,3,2-dioxaborinane

: 1192765-31-3
2-(2-chloro-4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)isoindoline-1,3-dione

Guidance literature:: With 1,1'-bis(diphenylphosphino)ferrocene; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); triethylamine; In toluene; at 100 ℃; for 18h; Inert atmosphere;
DOI:10.1021/ol902155e