3-benzyl-2,5-dichlorothiophene

Base Information

• Chemical Name: 3-benzyl-2,5-dichlorothiophene
• CAS No.: 77959-12-7
• Molecular Formula: C₁₁H₈Cl₂S
• Molecular Weight: 243.157
• Mol file: 77959-12-7.mol

Synonyms:

Chemical Property of 3-benzyl-2,5-dichlorothiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-benzyl-2,5-dichlorothiophene

There total 1 articles about 3-benzyl-2,5-dichlorothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

2,5-dichloro-3-chloromethyl-thiophene (10095-91-7) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 3-benzyl-2,5-dichlorothiophene (77959-12-7) + 3-benzyl-2-chloro-4-phenylthiophene (77959-11-6)

Guidance literature:

With aluminium trichloride; 1.0 mole AlCl₃; 1.) -5 deg C, 10 min, 2.) room temperature, 90 min;

DOI:10.1246/cl.1981.399

Reference yield:

3-benzyl-2,5-dichlorothiophene (77959-12-7) → 3-benzyl-4-phenylthiophene (77959-14-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum chloride / 1.) -5 deg C, 10 min, 2.) r. t., 90 min

2: Raney nickel

With aluminium trichloride; nickel;

DOI:10.1246/cl.1981.399

Reference yield:

3-benzyl-2,5-dichlorothiophene (77959-12-7) → 4-Benzyl-2-chloro-3-phenyl-thiophene (77959-15-0)

Guidance literature:

Multi-step reaction with 3 steps

1: aluminum chloride / 1.) -5 deg C, 10 min, 2.) r. t., 90 min

2: Raney nickel

3: sulfuryl chloride

With aluminium trichloride; sulfuryl dichloride; nickel;

DOI:10.1246/cl.1981.399

upstream raw materials:

2,5-dichloro-3-chloromethyl-thiophene

benzene

Downstream raw materials:

3-benzyl-4-phenylthiophene

4-Benzyl-2-chloro-3-phenyl-thiophene