(2S,4S)-2-allyl-5-O-triphenylmethyl pentan-4-olide

Base Information

• Chemical Name: (2S,4S)-2-allyl-5-O-triphenylmethyl pentan-4-olide
• CAS No.: 81019-78-5
• Molecular Formula: C₂₇H₂₆O₃
• Molecular Weight: 398.502
• Mol file: 81019-78-5.mol

Synonyms:

Chemical Property of (2S,4S)-2-allyl-5-O-triphenylmethyl pentan-4-olide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (2S,4S)-2-allyl-5-O-triphenylmethyl pentan-4-olide

There total 2 articles about (2S,4S)-2-allyl-5-O-triphenylmethyl pentan-4-olide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-(3R,5S)-3-allyl-5-trityloxymethyltetrahydrofuran-2-one (75652-70-9) → (2S,4S)-2-allyl-5-O-triphenylmethyl pentan-4-olide (81019-78-5)

Guidance literature:

With sodium sulfate; lithium diisopropyl amide; Yield given. Multistep reaction; 1.) -78 deg C; 2.) THF -78 deg C;

DOI:10.1246/cl.1982.733

Reference yield:

allyl bromide (106-95-6) + (5S)-5-[(trityloxy)methyl]tetrahydro-2-furanone → (+)-(3R,5S)-3-allyl-5-trityloxymethyltetrahydrofuran-2-one (75652-70-9) + (2S,4S)-2-allyl-5-O-triphenylmethyl pentan-4-olide (81019-78-5)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, 15 min, -76 deg C; 2.) THF, -76 deg C, warmed up to -30 deg C in 3 h;

upstream raw materials:

(+)-(3R,5S)-3-allyl-5-trityloxymethyltetrahydrofuran-2-one

allyl bromide