1H-Pyrrole-2-carboxylic acid, 1-[2-[[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phen yl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, methyl ester, (S)-

Base Information

Chemical Name:1H-Pyrrole-2-carboxylic acid, 1-[2-[[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phen yl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, methyl ester, (S)-
CAS No.:142219-21-4
Molecular Formula:C₃₂H₃₃N₅O₃
Molecular Weight:535.646
Hs Code.:

1H-Pyrrole-2-carboxylic acid,
1-[2-[[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phen
yl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, methyl ester, (S)-

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Chemical Property of 1H-Pyrrole-2-carboxylic acid, 1-[2-[[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phen yl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, methyl ester, (S)-

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Technology Process of 1H-Pyrrole-2-carboxylic acid, 1-[2-[[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phen yl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, methyl ester, (S)-

There total 3 articles about 1H-Pyrrole-2-carboxylic acid, 1-[2-[[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phen yl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, methyl ester, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39658-49-6
2,5-dimethoxy-tetrahydro-furan-2-carboxylic acid methyl ester

: 142219-21-4
1-{(S)-1-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenylcarbamoyl]-2-phenyl-ethyl}-1H-pyrrole-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 41 percent / NaOAc, HOAc / 0.5 h / Heating

2: (CH₃)3CCOCl, DMAP / tetrahydrofuran

With dmap; sodium acetate; pivaloyl chloride; acetic acid; In tetrahydrofuran;
DOI:10.1021/jm00064a007

Reference yield:

: 63-91-2,25191-15-5,658-69-5,67675-33-6
L-phenylalanine

: 142219-21-4
1-{(S)-1-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenylcarbamoyl]-2-phenyl-ethyl}-1H-pyrrole-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 41 percent / NaOAc, HOAc / 0.5 h / Heating

2: (CH₃)3CCOCl, DMAP / tetrahydrofuran

With dmap; sodium acetate; pivaloyl chloride; acetic acid; In tetrahydrofuran;
DOI:10.1021/jm00064a007