3-(4-Aminophenyl)-2-formamidopropanoic acid

Base Information

• Chemical Name: 3-(4-Aminophenyl)-2-formamidopropanoic acid
• CAS No.: 6949-62-8
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.217
• DSSTox Substance ID: DTXSID10409388
• NSC Number: 22693
• Mol file: 6949-62-8.mol

Synonyms:6949-62-8;3-(4-aminophenyl)-2-formamidopropanoic acid;DTXSID10409388;NSC22693;NSC-22693

Chemical Property of 3-(4-Aminophenyl)-2-formamidopropanoic acid

Chemical Property:

• XLogP3: 0.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 208.08479225
• Heavy Atom Count: 15
• Complexity: 225

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC(C(=O)O)NC=O)N

Technology Process of 3-(4-Aminophenyl)-2-formamidopropanoic acid

There total 2 articles about 3-(4-Aminophenyl)-2-formamidopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-formyl-4-nitro-phenylalanine (6949-60-6) → 4-amino-N-formyl-phenylalanine (6949-62-8)

Guidance literature:

With palladium on activated charcoal; water; Hydrogenation;

DOI:10.1039/jr9540002409

Reference yield:

4-nitrophenylalanine (1991-83-9,2922-40-9,56613-61-7,949-99-5) → 4-amino-N-formyl-phenylalanine (6949-62-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid anhydride

2: palladium/charcoal; H₂O / Hydrogenation

With palladium on activated charcoal; water; acetic anhydride;

DOI:10.1039/jr9540002409

upstream raw materials:

N-formyl-4-nitro-phenylalanine

4-nitrophenylalanine