N^α-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester

Base Information

• Chemical Name: N^α-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester
• CAS No.: 151145-33-4
• Molecular Formula: C₆₈H₅₉Cl₆F₅NO₂₄P
• Molecular Weight: 1612.89
• Mol file: 151145-33-4.mol

Synonyms:

Chemical Property of N^α-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester

There total 1 articles about N^α-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nα-(9-fluorenylmethoxycarbonyl)-L-threonine pentafluorophenyl ester (86061-06-5) + C43H42BrCl6O19P (150935-71-0) → Nα-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester (151145-33-4)

Guidance literature:

With 2,4,6-trimethyl-pyridine; silver trifluoromethanesulfonate; Yield given. Multistep reaction; 1.) CH₂Cl₂, -40 deg C, 1 h, 2.) 20 deg C;

Reference yield:

acetic anhydride (108-24-7) + Nα-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester (151145-33-4) + Nε-<2-(tert-butoxycarbonylamino)benzoyl>-Nα-(fluoren-9-ylmethoxycarbonyl)-L-lysine pentafluorophenyl ester (159322-60-8) → C109H118Cl12N6O45P2

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/S0968-0896(96)00194-0

Reference yield:

Fmoc-L-Lys(Boc)-OPfp (86060-98-2) + N-(9-fluorenylmethoxycarbonyl)-D-alanine (35661-38-2,35661-39-3,79990-15-1,136132-75-7) + (S)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(allyloxy)-4-oxobutanoic acid (144120-53-6) + Nα-(Fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-<2,3,4-tri-O-benzoyl-6-O-bis-(2,2,2-trichloroethoxy)phosphoryl-α-D-mannopyranosyl>-α-D-mannopyranosyl>-L-threonine pentafluorophenyl Ester (151145-33-4) → C110H124Cl12N8O47P2

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/S0968-0896(96)00194-0

upstream raw materials:

N^α-(9-fluorenylmethoxycarbonyl)-L-threonine pentafluorophenyl ester

C₄₃H₄₂BrCl₆O₁₉P