(S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

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Chemical Name:(S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester
CAS No.:37963-39-6
Molecular Formula:C₄₇H₆₅N₇O₁₂
Molecular Weight:920.073
Hs Code.:

(S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

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Chemical Property of (S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

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Technology Process of (S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

There total 1 articles about (S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3392-12-9
Boc-Val-ONSu

: 37963-39-6
(S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: stepwise elongation method using Boc-amin acid-OSu

2: 1-ethyl-3-(dimethylaminopropyl)-carbodiimide

With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
DOI:10.1016/S0040-4039(00)78991-X

Reference yield:

: 37963-39-6
(S)-1-((R)-2-{(S)-2-[(S)-5-Benzyloxycarbonylamino-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

: 15207-29-1
Cyclo[(Val-Orn-(Cbz)-Leu-DPhe-Pro)2]

: 15109-75-8
Z-semigramicidin S

Guidance literature:: With trifluoroacetic acid; Yield given. Multistep reaction. Yields of byproduct given; 2.) pyridine, 25 deg C, 1d;
DOI:10.1016/S0040-4039(00)78991-X