2-Oxazolidinone, 3-[1-oxo-5-(phenylmethoxy)pentyl]-4-(phenylmethyl)-, (4S)-

Base Information

Chemical Name:2-Oxazolidinone, 3-[1-oxo-5-(phenylmethoxy)pentyl]-4-(phenylmethyl)-, (4S)-
CAS No.:142945-19-5
Molecular Formula:C22H25NO4
Molecular Weight:367.43800
Hs Code.:
Mol file:142945-19-5.mol

Synonyms:4(S)-(benzyl)-3-(5-benzyloxy-1-oxopentyl)-2-oxazolidinone;(S)-4-Benzyl-3-(5-benzyloxy-pentanoyl)-oxazolidin-2-one;(S)-4-benzyl-3-[5-(benzyloxy)pentanoyl]oxazolidin-2-one;

Suppliers and Price of 2-Oxazolidinone, 3-[1-oxo-5-(phenylmethoxy)pentyl]-4-(phenylmethyl)-, (4S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Oxazolidinone, 3-[1-oxo-5-(phenylmethoxy)pentyl]-4-(phenylmethyl)-, (4S)-

Chemical Property:

PSA：55.84000
LogP:3.90150

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Oxazolidinone, 3-[1-oxo-5-(phenylmethoxy)pentyl]-4-(phenylmethyl)-, (4S)-

There total 8 articles about 2-Oxazolidinone, 3-[1-oxo-5-(phenylmethoxy)pentyl]-4-(phenylmethyl)-, (4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 128329-72-6
5-(phenylmethoxy)pentanoic acid chloride

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 142945-19-5
(4S)-4-benzyl-3-[5-(benzyloxy)pentanoyl]oxazolidin-2-one

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -80 ℃; for 2h;
DOI:10.1002/1522-2675(200211)85:11<4086::AID-HLCA4086>3.0.CO;2-7

Reference yield: 85.0%

: 64740-39-2
5-benzyloxypentanoic acid

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 142945-19-5
(4S)-4-benzyl-3-[5-(benzyloxy)pentanoyl]oxazolidin-2-one

Guidance literature:: 5-benzyloxypentanoic acid; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at -20 ℃; for 1h;

With lithium chloride; In tetrahydrofuran; at -20 ℃; for 0.166667h;

(S)-4-Benzyl-2-oxazolidinone; In tetrahydrofuran; at -20 - 0 ℃; for 3h;
DOI:10.14233/ajchem.2016.19475

Reference yield:

: 64740-39-2
5-benzyloxypentanoic acid

: 142945-19-5
(4S)-4-benzyl-3-[5-(benzyloxy)pentanoyl]oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride; DMF / toluene / 3.75 h / 20 - 60 °C

2: 86 percent / BuLi / tetrahydrofuran; hexane / 2 h / -80 °C

With n-butyllithium; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; hexane; toluene;
DOI:10.1002/1522-2675(200211)85:11<4086::AID-HLCA4086>3.0.CO;2-7