2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen

Base Information

• Chemical Name: 2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen
• CAS No.: 52853-48-2
• Molecular Formula: C₁₂H₁₂BrClN₂O₃
• Molecular Weight: 347.596
• Mol file: 52853-48-2.mol

Synonyms:

Chemical Property of 2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen

There total 3 articles about 2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-2-nitrotoluene (5367-26-0) → 2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen (52853-48-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 180 - 190 °C

2: phenoxymethyl-oxirane

With Phenyl glycidyl ether;

DOI:10.1002/jhet.5570110236

Reference yield:

2-chloro-6-methylaniline (87-63-8) → 2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen (52853-48-2)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂O₂, H₂SO₄, Ac₂O

2: 180 - 190 °C

3: phenoxymethyl-oxirane

With sulfuric acid; Phenyl glycidyl ether; dihydrogen peroxide; acetic anhydride;

DOI:10.1002/jhet.5570110236

Reference yield:

trans-3-Chlor-2-nitro-β-dimethylamino-styrol (52853-47-1) + 2-Bromoacetyl bromide (598-21-0) → 2-Bromacetyl-2-(3-chlor-2-nitrophenyl)-1-dimethylaminoethylen (52853-48-2)

Guidance literature:

With Phenyl glycidyl ether;

DOI:10.1002/jhet.5570110236

upstream raw materials:

trans-3-Chlor-2-nitro-β-dimethylamino-styrol

2-Bromoacetyl bromide

3-chloro-2-nitrotoluene

2-chloro-6-methylaniline

Refernces