2-(2-Chlorophenyl)-3-nitrochromen-4-one

Base Information

Chemical Name:2-(2-Chlorophenyl)-3-nitrochromen-4-one
CAS No.:143468-14-8
Molecular Formula:C15H8ClNO4
Molecular Weight:301.68100
Hs Code.:
DSSTox Substance ID:DTXSID201238589
Nikkaji Number:J479.403F
Mol file:143468-14-8.mol

Synonyms:143468-14-8;2-(2-Chlorophenyl)-3-nitrochromen-4-one;4H-1-Benzopyran-4-one,2-(2-chlorophenyl)-3-nitro-(9CI);4h-1-benzopyran-4-one,2-(2-chlorophenyl)-3-nitro-;DTXSID201238589;2-(2-Chlorophenyl)-3-nitro-4H-1-benzopyran-4-one

Suppliers and Price of 2-(2-Chlorophenyl)-3-nitrochromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-(2-Chlorophenyl)-3-nitrochromen-4-one

Chemical Property:

PSA：76.03000
LogP:4.54480
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:301.0141854
Heavy Atom Count:21
Complexity:485

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)C(=C(O2)C3=CC=CC=C3Cl)[N+](=O)[O-]

Technology Process of 2-(2-Chlorophenyl)-3-nitrochromen-4-one

There total 2 articles about 2-(2-Chlorophenyl)-3-nitrochromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 143468-32-0
(2S,3R)-3-Chloro-2-(2-chloro-phenyl)-3-nitro-chroman-4-one

: 143468-14-8
2-(2-Chloro-phenyl)-3-nitro-chromen-4-one

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; for 0.333333h;
DOI:10.1055/s-1992-26198

Reference yield:

: 127143-33-3
3-chloro-2-(2-chloro-phenyl)-3,4-dihydro-4-hydroxy-3-nitro-2H-1-benzopyran

: 143468-14-8
2-(2-Chloro-phenyl)-3-nitro-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / pyridinium chlorochromate (PCC) / CH₂Cl₂ / 8 h / Irradiation; r.t. to 55 deg C

2: 82 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / tetrahydrofuran / 0.33 h

With 1,8-diazabicyclo[5.4.0]undec-7-ene; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;
DOI:10.1055/s-1992-26198

Reference yield: 90.0%

: 143468-14-8
2-(2-Chloro-phenyl)-3-nitro-chromen-4-one

: 3-Amino-2-(2-chloro-phenyl)-chromen-4-one

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In 1,4-dioxane; for 16h;
DOI:10.1016/S0223-5234(97)84363-2