1,1'-Biphenyl, 2,2'-diiodo-4,4'-dimethyl-

Base Information

• Chemical Name: 1,1'-Biphenyl, 2,2'-diiodo-4,4'-dimethyl-
• CAS No.: 14376-78-4
• Molecular Formula: C₁₄H₁₂I₂
• Molecular Weight: 434.058
• Mol file: 14376-78-4.mol

Synonyms:2,2'-Diiod-4,4'-dimethyl-biphenyl;2,2'-Diiodo-4,4'-dimethylbiphenyl;2,2'-Diiodo-4,4'-dimethyl-1,1'-biphenyl;2,2'-Dijod-4,4'-dimethyl-biphenyl;1,1'-Biphenyl,2,2'-diiodo-4,4'-dimethyl;

Chemical Property of 1,1'-Biphenyl, 2,2'-diiodo-4,4'-dimethyl-

Chemical Property:

• PSA: 0.00000
• LogP: 5.17960

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1'-Biphenyl, 2,2'-diiodo-4,4'-dimethyl-

There total 1 articles about 1,1'-Biphenyl, 2,2'-diiodo-4,4'-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.3%

4,4′-dimethyl-[1,1′-biphenyl]-2,2′-diamine (59517-21-4) → 3,8-Dimethylbenzocinnolin (52143-63-2) + 2,2'-diiodo-4,4'-dimethyl-1,1'-biphenyl (14376-78-4) + 2-iodonio-4,4'-dimethyl-1,1'-biphenyl iodide

Guidance literature:

4,4′-dimethyl-[1,1′-biphenyl]-2,2′-diamine; With hydrogenchloride; sodium nitrite; at 2 ℃; for 0.25h;

With potassium iodide; In water; at 20 ℃; for 2h;

DOI:10.1002/1522-2675(200211)85:11<3748::AID-HLCA3748>3.0.CO;2-0

Reference yield:

2,2'-diiodo-4,4'-dimethyl-1,1'-biphenyl (14376-78-4) → 5-(2-isopropyl-phenyl)-3,7,3',7'-tetramethyl-5H-5λ5-[5,5']spirobi(benzo[b]phosphindole) (22454-21-3)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) nBuLi, Et₂O, (ii) /BRN= 2833319/

2: dimethylformamide

3: (i) nBuLi, Et₂O, (ii) /BRN= 866039/

In N,N-dimethyl-formamide;

DOI:10.1021/ja00824a014

Reference yield:

2,2'-diiodo-4,4'-dimethyl-1,1'-biphenyl (14376-78-4) → 2-Isopropyl-(4,4'-dimethyl-2,2'-biphenylen)phosphin-tosylimin

Guidance literature:

Multi-step reaction with 2 steps

1: (i) nBuLi, Et₂O, (ii) /BRN= 2833319/

2: dimethylformamide

In N,N-dimethyl-formamide;

DOI:10.1021/ja00824a014

upstream raw materials:

4,4′-dimethyl-[1,1′-biphenyl]-2,2′-diamine

Downstream raw materials:

3,7-dimethyl-5-phenyl-5H-benzo[b]phosphindole

5-(2-isopropyl-phenyl)-3,7,3',7'-tetramethyl-5H-5λ⁵-[5,5']spirobi(benzo[b]phosphindole)

3,7,3',7'-tetramethyl-5-(2,4,6-triisopropyl-phenyl)-5H-5λ⁵-[5,5']spirobi(benzo[b]phosphindole)

3,7-dimethyl-5-(2-phenyl-naphthalen-1-yl)-5H-dibenzoarsole