4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine

Base Information

• Chemical Name: 4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine
• CAS No.: 116691-39-5
• Molecular Formula: C₁₉H₁₈N₄O₄S
• Molecular Weight: 398.442
• Mol file: 116691-39-5.mol

Synonyms:

Chemical Property of 4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine

There total 2 articles about 4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(morpholinosulfonyl)aniline (21626-70-0) → 4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine (116691-39-5)

Guidance literature:

With acetic acid; Multistep reaction; 1) diazotisation, 2) 0 deg C;

Reference yield:

8-quinolinol (148-24-3,24804-14-6) + 4-(morpholinosulfonyl)aniline (21626-70-0) → 4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine (116691-39-5)

Guidance literature:

With sodium hydroxide; acetic acid; sodium nitrite; Multistep reaction; 1) 0 deg C 2) 3 d;

Reference yield:

4-<8-hydroxy-5-quinolylazo>benzenesulphonamyl morpholine (116691-39-5) + cobalt(II) chloride (7646-79-9,14543-09-0,16413-89-1) → Co(C19H17N4O4S)2 (134979-33-2)

Guidance literature:

In ethanol; byproducts: hydrochloric acid; mixing alc. soln. of org. ligand with CoCl2 (molar ratio 2:1) with stirring, pptn.; elem. anal.;

upstream raw materials:

8-quinolinol

4-(morpholinosulfonyl)aniline

Downstream raw materials:

Co(C₁₉H₁₇N₄O₄S)2

Hg(C₁₉H₁₇N₄O₄S)2

Ni(C₁₉H₁₇N₄O₄S)2

Refernces

• 1、 Hafez, Ali A. A. Abdel,Awad, Ibrahim M. A.,Hassan, Khairy M.. "STUDIES ON 4-(8-HYDROXY-5-QUINOLYLAZO)BENZENESULFONAMIDES AND THEIR METAL CHELATES AS POTENTIAL DRUGS". . p. 2753 - 2757. Retrieved 2007/10/02.