2-(Dichloromethyl)imidazo[1,2-a]pyridine

Base Information

Chemical Name:2-(Dichloromethyl)imidazo[1,2-a]pyridine
CAS No.:143982-35-8
Molecular Formula:C8H6Cl2N2
Molecular Weight:201.05300
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90465063
Nikkaji Number:J1.929.638E
Wikidata:Q82290733
Mol file:143982-35-8.mol

Synonyms:2-(Dichloromethyl)imidazo[1,2-a]pyridine;143982-35-8;SCHEMBL21045066;DTXSID90465063;3-(4-Acetylaminobenzoyl)propanoicacid;AKOS015995100;G11936

Suppliers and Price of 2-(Dichloromethyl)imidazo[1,2-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-dichloromethyl-imidazo[1,2-a]pyridine
50mg
$ 75.00

Chemenu
2-(dichloromethyl)imidazo[1,2-a]pyridine 95%
1g
$ 729.00

Chemcia Scientific
2-Dichloromethyl-imidazo[1,2-a]pyridine 92%
0.5 G
$ 125.00

American Custom Chemicals Corporation
2-(DICHLOROMETHYL)IMIDAZO-[1,2-A]PYRIDINE 95.00%
5MG
$ 496.97

Alichem
2-(Dichloromethyl)imidazo[1,2-a]pyridine
1g
$ 671.96

AccelPharmtech
2-(dichloromethyl)-Imidazo[1,2-a]pyridine 97.00%
25G
$ 3120.00

AccelPharmtech
2-(dichloromethyl)-Imidazo[1,2-a]pyridine 97.00%
1G
$ 1530.00

Total 5 raw suppliers

Chemical Property of 2-(Dichloromethyl)imidazo[1,2-a]pyridine

Chemical Property:

PSA：17.30000
LogP:2.81050
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:199.9908036
Heavy Atom Count:12
Complexity:163

Purity/Quality:

98%min ^*data from raw suppliers

2-dichloromethyl-imidazo[1,2-a]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC(=CN2C=C1)C(Cl)Cl

Technology Process of 2-(Dichloromethyl)imidazo[1,2-a]pyridine

There total 2 articles about 2-(Dichloromethyl)imidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 504-29-0
2-aminopyridine

: 921-03-9
1,1,3-trichloroacetone

: 118000-43-4
imidazo[1,2-a]pyridine-2-carbaldehyde

: 143982-35-8
2-dichloromethylimidazo<1,2-a>pyridine

: 143982-36-9
2-diethoxymethylimidazo[1,2-a]pyridine

Guidance literature:: In 1,2-dimethoxyethane; for 4h; Ambient temperature;
DOI:10.1002/jhet.5570290403

Reference yield: 71.0%

: 504-29-0
2-aminopyridine

: 921-03-9
1,1,3-trichloroacetone

: 143982-35-8
2-dichloromethylimidazo<1,2-a>pyridine

Guidance literature:: 2-aminopyridine; 1,1,3-trichloroacetone; In 1,2-dimethoxyethane; at 20 ℃; for 4h;

In ethanol; for 12h; Heating;
DOI:10.3987/com-01-9347

Reference yield:

: 143982-35-8
2-dichloromethylimidazo<1,2-a>pyridine

: N-(2-(cyclohexylamino)-1-(imidazo[1,2-a]pyridin-2-yl)-2-oxoethyl)-N-(4-methoxybenzyl)propiolamide

Guidance literature:: Multi-step reaction with 2 steps

1: calcium carbonate / water / 1 h / Reflux

2: sodium carbonate / methanol / 20 °C

With sodium carbonate; calcium carbonate; In methanol; water; 2: |Ugi Condensation;
DOI:10.1002/ejoc.201500270