3-cyclopentyloxy-4-methoxy-N-(2-methylsulfanylphenyl)benzamide

Base Information

Chemical Name:3-cyclopentyloxy-4-methoxy-N-(2-methylsulfanylphenyl)benzamide
CAS No.:144035-58-5
Molecular Formula:C20H23NO3S
Molecular Weight:357.46700
Hs Code.:
DSSTox Substance ID:DTXSID10438390
Nikkaji Number:J588.900F
Wikidata:Q82254122
ChEMBL ID:CHEMBL47957
Mol file:144035-58-5.mol

Synonyms:144035-58-5;CHEMBL47957;3-cyclopentyloxy-4-methoxy-N-(2-methylsulfanylphenyl)benzamide;SCHEMBL73091;DTXSID10438390;BDBM50041841;N-[2-(Methylthio)phenyl]-3-(cyclopentyloxy)-4-methoxybenzamide;3-Cyclopentyloxy-4-methoxy-N-(2-methylsulfanyl-phenyl)-benzamide

Suppliers and Price of 3-cyclopentyloxy-4-methoxy-N-(2-methylsulfanylphenyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-cyclopentyloxy-4-methoxy-N-(2-methylsulfanylphenyl)benzamide

Chemical Property:

PSA：76.35000
LogP:5.37480
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:357.13986477
Heavy Atom Count:25
Complexity:427

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(=O)NC2=CC=CC=C2SC)OC3CCCC3

Technology Process of 3-cyclopentyloxy-4-methoxy-N-(2-methylsulfanylphenyl)benzamide

There total 6 articles about 3-cyclopentyloxy-4-methoxy-N-(2-methylsulfanylphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2987-53-3
2-(Methylthio)aniline

: 144036-19-1
3-cyclopentyloxy-4-methoxy benzoic acid chloride

: 144035-58-5
N-(2-methylthiophenyl)-3-cyclopentyloxy-4-methoxybenzamide

Guidance literature:: With triethylamine; In dichloromethane; at 60 ℃; for 5h;
DOI:10.1021/jm00037a021

Reference yield:

: 621-59-0
isovanillin

: 144035-58-5
N-(2-methylthiophenyl)-3-cyclopentyloxy-4-methoxybenzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 81 percent / K₂CO₃, KI / dimethylformamide / 21 h / 65 °C

2: 92 percent / sulfamic acid, aq. AcOH, aq. NaClO₂ / 1 h / Ambient temperature

3: 98 percent / SOCl₂ / toluene; dimethylformamide / 5 h / Heating

4: Et₃N / CH₂Cl₂ / 5 h / 60 °C

With sodium chlorite; thionyl chloride; aminosulfonic acid; potassium carbonate; acetic acid; triethylamine; potassium iodide; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00037a021

Reference yield:

: 137-43-9
Cyclopentyl bromide

: 144035-58-5
N-(2-methylthiophenyl)-3-cyclopentyloxy-4-methoxybenzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 81 percent / K₂CO₃, KI / dimethylformamide / 21 h / 65 °C

2: 92 percent / sulfamic acid, aq. AcOH, aq. NaClO₂ / 1 h / Ambient temperature

3: 98 percent / SOCl₂ / toluene; dimethylformamide / 5 h / Heating

4: Et₃N / CH₂Cl₂ / 5 h / 60 °C

With sodium chlorite; thionyl chloride; aminosulfonic acid; potassium carbonate; acetic acid; triethylamine; potassium iodide; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00037a021