Stigmast-5-en-7-one,3-hydroxy-, (3b,24x)-

Base Information

• Chemical Name: Stigmast-5-en-7-one,3-hydroxy-, (3b,24x)-
• CAS No.: 88548-08-7
• Molecular Formula: C₂₉H₄₈O₂
• Molecular Weight: 428.699
• Mol file: 88548-08-7.mol

Synonyms:Sepesteonol

Chemical Property of Stigmast-5-en-7-one,3-hydroxy-, (3b,24x)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Stigmast-5-en-7-one,3-hydroxy-, (3b,24x)-

There total 10 articles about Stigmast-5-en-7-one,3-hydroxy-, (3b,24x)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

7-keto-β-sitosterol acetate → 3β-hydroxystigmast-5-en-7-one (2034-74-4,75521-66-3,88548-08-7,145163-97-9)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 2h;

DOI:10.1021/jf506361r

Reference yield: 97.0%

(24R)-3β-acetoxystigmast-5-en-7-one (18376-53-9) → 3β-hydroxystigmast-5-en-7-one (2034-74-4,75521-66-3,88548-08-7,145163-97-9)

Guidance literature:

With sodium methylate; In methanol; chloroform; at 20 ℃; for 2h;

DOI:10.1021/jm1007769

Reference yield: 68.0%

β-sitosterol (83-46-5) → 3β-hydroxystigmast-5-en-7-one (2034-74-4,75521-66-3,88548-08-7,145163-97-9)

Guidance literature:

With N-hydroxyphthalimide; oxygen; cobalt(II) acetate; manganese(II) acetate; In 1,4-dioxane; at 20 ℃; for 8h; under 760.051 Torr;

DOI:10.1039/b915737a

upstream raw materials:

(24R)-3β-acetoxystigmast-5-en-7-one

22,23-dihydro-i-stigmasterol methyl ether

β-sitosterol

stigmast-5-en-3-yl acetate

Downstream raw materials:

5-stigmasten-3β,7β-diol

22-dihydrospinasterol

Refernces

• 1、 Bus, Katarzyna,Ofiara, Karol,Sitkowski, Jerzy,Szterk, Arkadiusz,Zmys?owski, Adam. "Synthesis and search for 3β,3′β-disteryl ethers after high-temperature treatment of sterol-rich samples". . . Retrieved 2020/06/08.
• 2、 Zhu, Yingdong,Soroka, Dominique,Sang, Shengmin. "Oxyphytosterols as active ingredients in wheat bran suppress human colon cancer cell growth: Identification, chemical synthesis, and biological evaluation". . p. 2267 - 2276. Retrieved 2015/03/14.