N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid

Base Information

• Chemical Name: N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid
• CAS No.: 15960-60-8
• Molecular Formula: C₃₈H₆₀ClN₇O₈S
• Molecular Weight: 810.455

Synonyms:

Chemical Property of N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid

There total 3 articles about N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) → N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid (15960-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) ClCO₂Et, nBu₃N, THF, (ii) /BRN= 6582053/

2: (i) HCl, AcOH, (ii) /BRN= 5681424/, DCC, Py

Reference yield:

S-β-Chlorallyl)-homocystein-amid → N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid (15960-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) ClCO₂Et, nBu₃N, THF, (ii) /BRN= 6582053/

2: (i) HCl, AcOH, (ii) /BRN= 5681424/, DCC, Py

Reference yield:

Boc-Ala-Phe-Ile-Gly-OH (3235-90-3) + N-Carbo-tert.-butoxy-Leu--homocystein-amid (15960-51-7) → N-tert.-Butoxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid-hydrochlorid (15960-60-8)

Guidance literature:

Multistep reaction; (i) HCl, AcOH, (ii) /BRN= 5681424/, DCC, Py;

upstream raw materials:

Boc-Ala-Phe-Ile-Gly-OH

N-Carbo-tert.-butoxy-Leu--homocystein-amid

N-tert-butoxycarbonyl-L-leucine

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