5-cyclohexyl-6-hydroxy-2,3-dihydro-1H-indene-1-carboxylic acid

Base Information

Chemical Name:5-cyclohexyl-6-hydroxy-2,3-dihydro-1H-indene-1-carboxylic acid
CAS No.:28998-48-3
Molecular Formula:C16H20 O3
Molecular Weight:260.3282
Hs Code.:
Mol file:28998-48-3.mol

Synonyms:1-Indancarboxylicacid, 5-cyclohexyl-6-hydroxy-, (?à)- (8CI); 1H-Indene-1-carboxylic acid, 5-cyclohexyl-2,3-dihydro-6-hydroxy-,(?à)-; (?à)-5-Cyclohexyl-6-hydroxyindan-1-carboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-cyclohexyl-6-hydroxy-2,3-dihydro-1H-indene-1-carboxylic acid

Chemical Property:

Vapor Pressure:1.42E-07mmHg at 25°C
Boiling Point:413.4°C at 760 mmHg
Flash Point:218°C
Density:1.237g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-cyclohexyl-6-hydroxy-2,3-dihydro-1H-indene-1-carboxylic acid

There total 5 articles about 5-cyclohexyl-6-hydroxy-2,3-dihydro-1H-indene-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36414-05-8
(4-cyclohexyl-phenyl)-succinic acid anhydride

: 28998-48-3
(+/-)-5-Cyclohexyl-6-hydroxyindan-1-carbonsaeure

Guidance literature:: Multi-step reaction with 4 steps

1: AlCl₃ / CH₂Cl₂

2: H₂, aq. HClO₄ / Pd-C / acetic acid

3: (i) aq. HNO₃, H₂SO₄, (ii) H₂, Raney-Ni, EtOH

4: (i) NaNO₂, aq. HCl, (ii) (heating)

With aluminium trichloride; perchloric acid; hydrogen; palladium on activated charcoal; In dichloromethane; acetic acid;
DOI:10.1021/jm00282a024

Reference yield:

: 28968-04-9
(+/-)-5-Cyclohexyl-3-oxo-1-indancarbonsaeure

: 28998-48-3
(+/-)-5-Cyclohexyl-6-hydroxyindan-1-carbonsaeure

Guidance literature:: Multi-step reaction with 3 steps

1: H₂, aq. HClO₄ / Pd-C / acetic acid

2: (i) aq. HNO₃, H₂SO₄, (ii) H₂, Raney-Ni, EtOH

3: (i) NaNO₂, aq. HCl, (ii) (heating)

With perchloric acid; hydrogen; palladium on activated charcoal; In acetic acid;
DOI:10.1021/jm00282a024