Flavone, 2',3,5,7-tetramethoxy-

Base Information

Chemical Name:Flavone, 2',3,5,7-tetramethoxy-
CAS No.:14585-15-0
Molecular Formula:C19H18O6
Molecular Weight:342.34300
Hs Code.:
DSSTox Substance ID:DTXSID801194418
Nikkaji Number:J117.958F
Mol file:14585-15-0.mol

Synonyms:Flavone, 2',3,5,7-tetramethoxy-;14585-15-0;2',3,5,7-Tetramethoxyflavone;2/',3,5,7-Tetramethoxyflavone;DTXSID801194418;3,5,7-Trimethoxy-2-(2-methoxyphenyl)-4H-chromen-4-one #;3,5,7-Trimethoxy-2-(2-methoxyphenyl)-4H-1-benzopyran-4-one

Suppliers and Price of Flavone, 2',3,5,7-tetramethoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Flavone, 2',3,5,7-tetramethoxy-

Chemical Property:

Melting Point:169-170 °C
Boiling Point:548.9±50.0 °C(Predicted)
PSA：67.13000
Density:1.29±0.1 g/cm3(Predicted)
LogP:3.49440
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:342.11033829
Heavy Atom Count:25
Complexity:516

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1C2=C(C(=O)C3=C(O2)C=C(C=C3OC)OC)OC

Technology Process of Flavone, 2',3,5,7-tetramethoxy-

There total 4 articles about Flavone, 2',3,5,7-tetramethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1385652-13-0
C₁₉H₂₀O₇

: 14585-15-0
3,5,7,2'-tetramethoxyflavone

Guidance literature:: With sulfuric acid; acetic acid; at 80 ℃; for 0.5h;
DOI:10.5012/bkcs.2012.33.4.1379

Reference yield:

: 500-99-2
3,5-dimethoxyphenol

: 14585-15-0
3,5,7,2'-tetramethoxyflavone

Guidance literature:: Multi-step reaction with 4 steps

1: aluminum (III) chloride / 1,1,2,2-tetrachloroethane / 20 °C

2: triethylamine / dichloromethane / 0 - 20 °C

3: lithium diisopropyl amide / tetrahydrofuran / 1 h / -15 - 0 °C / Inert atmosphere

4: sulfuric acid; acetic acid / 0.5 h / 80 °C

With aluminum (III) chloride; sulfuric acid; acetic acid; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; 1,1,2,2-tetrachloroethane;
DOI:10.5012/bkcs.2012.33.4.1379

Reference yield:

: 17874-42-9
2'-hydroxy-2,4',6'-trimethoxyacetophenone

: 14585-15-0
3,5,7,2'-tetramethoxyflavone

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: lithium diisopropyl amide / tetrahydrofuran / 1 h / -15 - 0 °C / Inert atmosphere

3: sulfuric acid; acetic acid / 0.5 h / 80 °C

With sulfuric acid; acetic acid; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;
DOI:10.5012/bkcs.2012.33.4.1379