1H-Pyrazole-4-carboxaldehyde, 5-chloro-3-methyl-1-phenyl-, hydrazone

Base Information

• Chemical Name: 1H-Pyrazole-4-carboxaldehyde, 5-chloro-3-methyl-1-phenyl-, hydrazone
• CAS No.: 146254-77-5
• Molecular Formula: C₁₁H₁₁ClN₄
• Molecular Weight: 234.688
• DSSTox Substance ID: DTXSID90351396
• Mol file: 146254-77-5.mol

Synonyms:146254-77-5;1H-Pyrazole-4-carboxaldehyde, 5-chloro-3-methyl-1-phenyl-, hydrazone;DTXSID90351396

Chemical Property of 1H-Pyrazole-4-carboxaldehyde, 5-chloro-3-methyl-1-phenyl-, hydrazone

Chemical Property:

• PSA: 56.20000
• LogP: 2.82700
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 234.0672241
• Heavy Atom Count: 16
• Complexity: 252

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NN(C(=C1C=NN)Cl)C2=CC=CC=C2

Technology Process of 1H-Pyrazole-4-carboxaldehyde, 5-chloro-3-methyl-1-phenyl-, hydrazone

There total 2 articles about 1H-Pyrazole-4-carboxaldehyde, 5-chloro-3-methyl-1-phenyl-, hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole (947-95-5) → 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde hydrazone (146254-77-5)

Guidance literature:

With hydrazine hydrate; at 180 ℃; im Rohr;

Reference yield:

5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole (947-95-5) + hydrazine hydrate (7803-57-8,79785-97-0) → 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde hydrazone (146254-77-5)

Guidance literature:

at 180 ℃; im Rohr;

Reference yield: 90.0%

5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde hydrazone (146254-77-5) → 3-methyl-1-phenylpyrazolo<2,3-d>pyrazoline

Guidance literature:

at 140 - 160 ℃;

upstream raw materials:

5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole

hydrazine hydrate