N-[4-(Hydrazinocarbonyl)phenyl]benzamide

Base Information

• Chemical Name: N-[4-(Hydrazinocarbonyl)phenyl]benzamide
• CAS No.: 146305-29-5
• Molecular Formula: C14H13N3O2
• Molecular Weight: 255.276
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID70350382
• Nikkaji Number: J3.608.243G
• Wikidata: Q82126294
• Mol file: 146305-29-5.mol

Synonyms:146305-29-5;N-[4-(HYDRAZINOCARBONYL)PHENYL]BENZAMIDE;N-[4-(hydrazinecarbonyl)phenyl]benzamide;N-(4-(Hydrazinecarbonyl)phenyl)benzamide;N-[4-(hydrazinylcarbonyl)phenyl]benzamide;N-(4-Hydrazinocarbonyl-phenyl)-benzamide;Oprea1_206098;Oprea1_807393;SCHEMBL2831786;DTXSID70350382;WFA30529;BBL023053;MFCD01028809;STK121456;AKOS000304482;VS-07315;Benzamide, N-(4-hydrazinocarbonylphenyl)-;CS-0269740;EN300-227934;SR-01000310363;N~1~-[4-(HYDRAZINOCARBONYL)PHENYL]BENZAMIDE;SR-01000310363-1

Chemical Property of N-[4-(Hydrazinocarbonyl)phenyl]benzamide

Chemical Property:

• Melting Point: 200 °C(Solv: methanol (67-56-1))
• PKA: 12.59±0.10(Predicted)
• PSA: 84.22000
• Density: 1.303±0.06 g/cm3(Predicted)
• LogP: 2.70660
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 255.100776666
• Heavy Atom Count: 19
• Complexity: 319

Purity/Quality:

98%min ^*data from raw suppliers

N-[4-(Hydrazinocarbonyl)phenyl]benzamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)C(=O)NN

Technology Process of N-[4-(Hydrazinocarbonyl)phenyl]benzamide

There total 16 articles about N-[4-(Hydrazinocarbonyl)phenyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-benzoylbenzocaine (736-40-3) → N-[4-(hydrazinylcarbonyl)phenyl]benzamide (146305-29-5)

Guidance literature:

With hydrazine hydrate; at 110 - 130 ℃; for 1h;

Reference yield:

tert-butyl 2-(4-benzamidobenzoyl)hydrazinecarboxylate → N-[4-(hydrazinylcarbonyl)phenyl]benzamide (146305-29-5)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1016/j.bmcl.2014.11.067

Reference yield:

N-benzyl-(4-benzyloxycarbonyl)benzamide → N-[4-(hydrazinylcarbonyl)phenyl]benzamide (146305-29-5)

Guidance literature:

With hydrazine hydrate; In methanol;

DOI:10.1134/S1068162020050052

upstream raw materials:

N-benzoylbenzocaine

benzoyl chloride

p-aminoethylbenzoate

hydrazine hydrate

Downstream raw materials:

C₁₇H₁₈N₄O₂S

C₂₃H₂₂N₄O₂S

C₂₁H₁₈N₄O₂S

1-[4-(benzoylamino)benzoyl]-4-(4-chlorophenyl)thiosemicarbazide