1,5-Dihydroxyxanthone

Base Information

• Chemical Name: 1,5-Dihydroxyxanthone
• CAS No.: 14686-65-8
• Molecular Formula: C13H8O4
• Molecular Weight: 228.204
• DSSTox Substance ID: DTXSID80420489
• Nikkaji Number: J167.422F
• Wikidata: Q82231778
• Pharos Ligand ID: NSXCTSFU9TU4
• Metabolomics Workbench ID: 44522
• ChEMBL ID: CHEMBL185686
• Mol file: 14686-65-8.mol

Synonyms:1,5-Dihydroxyxanthone;14686-65-8;1,5-dihydroxyxanthen-9-one;1,5-DIHYDROXY-9H-XANTHEN-9-ONE;9H-Xanthen-9-one, 1,5-dihydroxy-;CHEMBL185686;1,5-Dihydroxy-xanthen-9-one;SCHEMBL15527312;DTXSID80420489;BDBM50155419;1,5-Dihydroxy-9H-xanthen-9-one, 9CI

Chemical Property of 1,5-Dihydroxyxanthone

Chemical Property:

• PSA: 70.67000
• LogP: 2.35740
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 228.04225873
• Heavy Atom Count: 17
• Complexity: 317

Purity/Quality:

Analysis control,98.0% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)O)OC3=CC=CC(=C3C2=O)O

Technology Process of 1,5-Dihydroxyxanthone

There total 3 articles about 1,5-Dihydroxyxanthone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.5%

methyl 2,6-dihydroxybenzoate (2150-45-0) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 1,5-dihydroxyxanthone (14686-65-8)

Guidance literature:

In diphenylether; for 6h; Heating;

Reference yield:

2,3',6-trihydroxybenzophenone (21554-76-7) → 1,5-dihydroxyxanthone (14686-65-8) + euxanthone (529-61-3)

Guidance literature:

With silver carbonate; In acetonitrile; at 100 ℃; for 2h; Reagent/catalyst; Solvent; Overall yield = 68 %; Inert atmosphere;

DOI:10.1002/chem.201603980

Reference yield:

→ 1,5-dihydroxyxanthone (14686-65-8)

Guidance literature:

DOI:10.1016/S0040-4039(00)70145-6 DOI:10.1039/j39700000392

upstream raw materials:

methyl 2,6-dihydroxybenzoate

benzene-1,2-diol

2,3',6-trihydroxybenzophenone