N,N-Diisopropyl-4-chlorobenzenesulfonamide

Base Information

• Chemical Name: N,N-Diisopropyl-4-chlorobenzenesulfonamide
• CAS No.: 14743-85-2
• Molecular Formula: C12H18ClNO2S
• Molecular Weight: 275.799
• DSSTox Substance ID: DTXSID00402828
• Nikkaji Number: J1.708.249C
• Wikidata: Q82206333
• Mol file: 14743-85-2.mol

Synonyms:14743-85-2;ST51017171;SCHEMBL2332262;DTXSID00402828;AKOS003268775;N,N-Diisopropyl-4-chlorobenzenesulfonamide

Chemical Property of N,N-Diisopropyl-4-chlorobenzenesulfonamide

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 275.0746777
• Heavy Atom Count: 17
• Complexity: 319

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)N(C(C)C)S(=O)(=O)C1=CC=C(C=C1)Cl

Technology Process of N,N-Diisopropyl-4-chlorobenzenesulfonamide

There total 1 articles about N,N-Diisopropyl-4-chlorobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-chloro-N,N-diisopropylbenzenesulfonamide (14743-85-2)

Guidance literature:

RSO2Cl, entspr. Amin;

Reference yield: 99.0%

4-chloro-N,N-diisopropylbenzenesulfonamide (14743-85-2) + n-tetradecylmagnesium chloride (110220-87-6) → N,N-diisopropyl-4-tetradecylbenzenesulfonamide

Guidance literature:

With 1,3-dimethyl-2-imidazolidinone; iron(III)-acetylacetonate; In tetrahydrofuran; at 0 ℃; for 3h;

DOI:10.1039/c8cy02374c

Reference yield: 97.0%

4-chloro-N,N-diisopropylbenzenesulfonamide (14743-85-2) + ethylmagnesium chloride (2386-64-3) → 4-ethyl-N,N-diisopropylbenzenesulfonamide

Guidance literature:

With 1-methyl-pyrrolidin-2-one; iron(III)-acetylacetonate; In tetrahydrofuran; at 0 ℃; for 0.166667h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.8b02886

Downstream raw materials:

(S)-2-methyl-1,2,3,4-tetrahydroquinoline

(R)-1,2,3,4-tetrahydroquinaldine

Refernces