2-Methyl-1-(4-methylphenyl)-3-nitroindol-6-ol

Base Information

Chemical Name:2-Methyl-1-(4-methylphenyl)-3-nitroindol-6-ol
CAS No.:147591-45-5
Molecular Formula:C₁₆H₁₄N₂O₃
Molecular Weight:282.299
Hs Code.:
DSSTox Substance ID:DTXSID101319693
Nikkaji Number:J2.638.378A
ChEMBL ID:CHEMBL1520241
Mol file:147591-45-5.mol

Synonyms:MLS000777392;2-methyl-1-(4-methylphenyl)-3-nitroindol-6-ol;SMR000413809;2-Methyl-3-nitro-1-p-tolyl-1H-indol-6-ol;CBMicro_007858;Oprea1_650711;cid_899976;SCHEMBL4066988;CHEMBL1520241;BDBM54390;DTXSID101319693;HMS2766A17;SMSF0012170;STL324804;AKOS022128688;CB10382;147591-45-5;2-methyl-3-nitro-1-(p-tolyl)indol-6-ol;BIM-0007825.P001;1-(p-tolyl)-2-methyl-3-nitro-6-hydroxyindole;2-methyl-1-(4-methylphenyl)-3-nitro-6-indolol;2-methyl-1-(4-methylphenyl)-3-nitro-indol-6-ol;2-methyl-1-(4-methylphenyl)-3-nitro-1H-indol-6-ol;BRD-K38166648-001-04-0

Suppliers and Price of 2-Methyl-1-(4-methylphenyl)-3-nitroindol-6-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Methyl-1-(4-methylphenyl)-3-nitroindol-6-ol

Chemical Property:

Melting Point:271 - 272 °C (ethanol)
PSA：70.98000
LogP:4.38430
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:282.10044231
Heavy Atom Count:21
Complexity:390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2C(=C(C3=C2C=C(C=C3)O)[N+](=O)[O-])C

Technology Process of 2-Methyl-1-(4-methylphenyl)-3-nitroindol-6-ol

There total 2 articles about 2-Methyl-1-(4-methylphenyl)-3-nitroindol-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 147591-39-7
((Z)-1-Methyl-2-nitro-vinyl)-p-tolyl-amine

: 106-51-4
p-benzoquinone

: 147591-45-5
1-(p-tolyl)-2-methyl-3-nitro-5-hydroxyindole

Guidance literature:: With acetic anhydride; acetic acid; at 20 ℃; for 36h;
DOI:10.1007/BF00529475

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 147591-45-5
1-(p-tolyl)-2-methyl-3-nitro-5-hydroxyindole

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / p-toluenesulfonic acid / dimethylformamide / 2 h / 20 °C

2: 39 percent / acetic acid, acetic anhydride / 36 h / 20 °C

With acetic anhydride; toluene-4-sulfonic acid; acetic acid; In N,N-dimethyl-formamide;
DOI:10.1007/BF00529475